A mild, phosphine-free method for the conversion of alcohols into halides (Cl, Br, I) via the corresponding O-alkyl isoureas
A mild, phosphine-free method for the conversion of alcohols into halides (Cl, Br, I) via the corresponding O-alkyl isoureas
A novel procedure for the conversion of primary and secondary alcohols into the corresponding alkyl chlorides, bromides and iodides is described. The transformation is high-yielding in the case of chlorides and bromides, tolerates a range of functional groups, and does not rely on the use of phosphines.
8143-8147
Li, Zhengning
ce4163f9-eb41-48e8-95e0-785fc3a12bf5
Crosignani, Stefano
aaa5cc3f-0b82-4d33-af01-59115c8bdff5
Linclau, Bruno
19b9cacd-b8e8-4c65-af36-6352cade84ba
2003
Li, Zhengning
ce4163f9-eb41-48e8-95e0-785fc3a12bf5
Crosignani, Stefano
aaa5cc3f-0b82-4d33-af01-59115c8bdff5
Linclau, Bruno
19b9cacd-b8e8-4c65-af36-6352cade84ba
Li, Zhengning, Crosignani, Stefano and Linclau, Bruno
(2003)
A mild, phosphine-free method for the conversion of alcohols into halides (Cl, Br, I) via the corresponding O-alkyl isoureas.
Tetrahedron Letters, 44 (44), .
(doi:10.1016/j.tetlet.2003.09.024).
Abstract
A novel procedure for the conversion of primary and secondary alcohols into the corresponding alkyl chlorides, bromides and iodides is described. The transformation is high-yielding in the case of chlorides and bromides, tolerates a range of functional groups, and does not rely on the use of phosphines.
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Published date: 2003
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Local EPrints ID: 37586
URI: http://eprints.soton.ac.uk/id/eprint/37586
ISSN: 0040-4039
PURE UUID: 50ad2681-b7d9-407b-ba23-55aba8bb94d4
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Date deposited: 24 May 2006
Last modified: 16 Mar 2024 03:15
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Author:
Zhengning Li
Author:
Stefano Crosignani
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