The University of Southampton
University of Southampton Institutional Repository

Microcirculation in the foot is augmented by neuromuscular stimulation via the common peroneal nerve in different lower limb postures: a potential treatment for leg ulcers

Microcirculation in the foot is augmented by neuromuscular stimulation via the common peroneal nerve in different lower limb postures: a potential treatment for leg ulcers
Microcirculation in the foot is augmented by neuromuscular stimulation via the common peroneal nerve in different lower limb postures: a potential treatment for leg ulcers
AIM:
Aim of the study was to examine the effects of the geko™ device (a portable electrical nerve stimulator) on microcirculatory flow on the dorsum of the foot, and whether this is influenced by lower limb postures and application of a plaster cast.
METHODS:
This was a cross-sectional, healthy cohort, open label, physiological response study. In 10 healthy volunteers, aged 19 to 24 years, laser Doppler fluxmetry measurements were made on the dorsum of the foot in four postures: standing (weight bearing and non-weight bearing) and supine lying (with the lower limb horizontal and then elevated). Measurements of flux were made both at rest and during stimulation with the geko™ device applied over the common peroneal nerve, at 1 Hz for 5 minutes in each posture. Repeat measurement were made after the application of a below knee plaster cast. Measures of flux were compared to basal levels assumed to be in supine with limb horizontal, with no cast and an inactive geko™ device.
RESULTS:
The geko™ device was effective in increasing microcirculation on the dorsum of the foot in all four postures (mean difference =141%, 95% CI 70%-212%, P=0.001). This effect was more pronounced than that of using a plaster alone (Mean increase in flux of 73%, 95% CI 22%-125%, P=0.01) or variances due to the hydrostatic effects of different postures (mean difference 17-27.6%, P>0.05). There was a 2 to 3 fold increase in flux when stimulation was delivered in combination with the plaster cast.
CONCLUSION:
Stimulation using the geko™ device augments microcirculation in the foot. The response is greater in lying and non-weight bearing than weight bearing standing but the most striking effect is when stimulation is combined with a plaster cast. The geko™ offers a potential means of promoting conditions favourable for wound healing, where treatment using compression may be contraindicated, such as arterial/mixed aetiology ulcers.
158-165
Warwick, David J.
d23cacce-41eb-42bd-b8cc-da6a3b837a9f
Shaikh, A.
1c8ce619-4e4f-4aff-b104-d6a7ac32d1cd
Worsley, Peter
6d33aee3-ef43-468d-aef6-86d190de6756
Gadola, Stephan D.
ef2fa6cf-2ccc-4fea-a7a5-cc03a9d13ab1
Bain, D.
f7a8aa36-3401-4911-b7d9-61215b2859ba
Tucker, A.
903f853e-d437-4f46-bb04-73b69fbd5b24
Stokes, M.
71730503-70ce-4e67-b7ea-a3e54579717f
Warwick, David J.
d23cacce-41eb-42bd-b8cc-da6a3b837a9f
Shaikh, A.
1c8ce619-4e4f-4aff-b104-d6a7ac32d1cd
Worsley, Peter
6d33aee3-ef43-468d-aef6-86d190de6756
Gadola, Stephan D.
ef2fa6cf-2ccc-4fea-a7a5-cc03a9d13ab1
Bain, D.
f7a8aa36-3401-4911-b7d9-61215b2859ba
Tucker, A.
903f853e-d437-4f46-bb04-73b69fbd5b24
Stokes, M.
71730503-70ce-4e67-b7ea-a3e54579717f

Warwick, David J., Shaikh, A., Worsley, Peter, Gadola, Stephan D., Bain, D., Tucker, A. and Stokes, M. (2015) Microcirculation in the foot is augmented by neuromuscular stimulation via the common peroneal nerve in different lower limb postures: a potential treatment for leg ulcers. International Angiology, 34 (2), 158-165. (PMID:25839841)

Record type: Article

Abstract

AIM:
Aim of the study was to examine the effects of the geko™ device (a portable electrical nerve stimulator) on microcirculatory flow on the dorsum of the foot, and whether this is influenced by lower limb postures and application of a plaster cast.
METHODS:
This was a cross-sectional, healthy cohort, open label, physiological response study. In 10 healthy volunteers, aged 19 to 24 years, laser Doppler fluxmetry measurements were made on the dorsum of the foot in four postures: standing (weight bearing and non-weight bearing) and supine lying (with the lower limb horizontal and then elevated). Measurements of flux were made both at rest and during stimulation with the geko™ device applied over the common peroneal nerve, at 1 Hz for 5 minutes in each posture. Repeat measurement were made after the application of a below knee plaster cast. Measures of flux were compared to basal levels assumed to be in supine with limb horizontal, with no cast and an inactive geko™ device.
RESULTS:
The geko™ device was effective in increasing microcirculation on the dorsum of the foot in all four postures (mean difference =141%, 95% CI 70%-212%, P=0.001). This effect was more pronounced than that of using a plaster alone (Mean increase in flux of 73%, 95% CI 22%-125%, P=0.01) or variances due to the hydrostatic effects of different postures (mean difference 17-27.6%, P>0.05). There was a 2 to 3 fold increase in flux when stimulation was delivered in combination with the plaster cast.
CONCLUSION:
Stimulation using the geko™ device augments microcirculation in the foot. The response is greater in lying and non-weight bearing than weight bearing standing but the most striking effect is when stimulation is combined with a plaster cast. The geko™ offers a potential means of promoting conditions favourable for wound healing, where treatment using compression may be contraindicated, such as arterial/mixed aetiology ulcers.

Full text not available from this repository.

More information

Published date: 1 April 2015
Organisations: Faculty of Medicine, Physical & Rehabilitation Health

Identifiers

Local EPrints ID: 376501
URI: http://eprints.soton.ac.uk/id/eprint/376501
PURE UUID: 112c8464-1831-4668-a577-4f2d04ec13c5
ORCID for Peter Worsley: ORCID iD orcid.org/0000-0003-0145-5042
ORCID for M. Stokes: ORCID iD orcid.org/0000-0002-4204-0890

Catalogue record

Date deposited: 29 Apr 2015 15:13
Last modified: 18 Feb 2021 17:11

Export record

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×