Measuring protein concentration with entangled photons
Measuring protein concentration with entangled photons
Optical interferometry is amongst the most sensitive techniques for precision measurement. By increasing the light intensity, a more precise measurement can usually be made. However, if the sample is light sensitive entangled states can achieve the same precision with less exposure. This concept has been demonstrated in measurements of known optical components. Here, we use two-photon entangled states to measure the concentration of a blood protein in an aqueous buffer solution. We use an opto-fluidic device that couples a waveguide interferometer with a microfluidic channel. These results point the way to practical applications of quantum metrology to light-sensitive samples.
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Crespi, Andrea
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Lobino, Mirko
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Matthews, Jonathan C.F.
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Politi, Alberto
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Neal, Chris R.
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Ramponi, Roberta
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Osellame, Roberto
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O'Brien, Jeremy L.
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5 June 2012
Crespi, Andrea
a58f3b10-5752-4fb8-8397-da25a4295164
Lobino, Mirko
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Matthews, Jonathan C.F.
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Politi, Alberto
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Neal, Chris R.
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Ramponi, Roberta
2651461b-750a-43cc-96df-817f55fe26ad
Osellame, Roberto
b0ef5741-488b-42ae-934a-1a3eb424a203
O'Brien, Jeremy L.
03208a26-089b-4212-b691-87f26cff783c
Crespi, Andrea, Lobino, Mirko, Matthews, Jonathan C.F., Politi, Alberto, Neal, Chris R., Ramponi, Roberta, Osellame, Roberto and O'Brien, Jeremy L.
(2012)
Measuring protein concentration with entangled photons.
Applied Physics Letters, 100 (23), .
(doi:10.1063/1.4724105).
Abstract
Optical interferometry is amongst the most sensitive techniques for precision measurement. By increasing the light intensity, a more precise measurement can usually be made. However, if the sample is light sensitive entangled states can achieve the same precision with less exposure. This concept has been demonstrated in measurements of known optical components. Here, we use two-photon entangled states to measure the concentration of a blood protein in an aqueous buffer solution. We use an opto-fluidic device that couples a waveguide interferometer with a microfluidic channel. These results point the way to practical applications of quantum metrology to light-sensitive samples.
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Accepted/In Press date: 11 May 2012
Published date: 5 June 2012
Organisations:
Quantum, Light & Matter Group
Identifiers
Local EPrints ID: 377102
URI: http://eprints.soton.ac.uk/id/eprint/377102
ISSN: 0003-6951
PURE UUID: 26f049a2-41aa-4ee4-a0d3-bb35b6322e74
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Date deposited: 26 May 2015 09:03
Last modified: 15 Mar 2024 03:49
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Contributors
Author:
Andrea Crespi
Author:
Mirko Lobino
Author:
Jonathan C.F. Matthews
Author:
Chris R. Neal
Author:
Roberta Ramponi
Author:
Roberto Osellame
Author:
Jeremy L. O'Brien
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