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Measuring protein concentration with entangled photons

Measuring protein concentration with entangled photons
Measuring protein concentration with entangled photons
Optical interferometry is amongst the most sensitive techniques for precision measurement. By increasing the light intensity, a more precise measurement can usually be made. However, if the sample is light sensitive entangled states can achieve the same precision with less exposure. This concept has been demonstrated in measurements of known optical components. Here, we use two-photon entangled states to measure the concentration of a blood protein in an aqueous buffer solution. We use an opto-fluidic device that couples a waveguide interferometer with a microfluidic channel. These results point the way to practical applications of quantum metrology to light-sensitive samples.
0003-6951
233704-1-233704-5
Crespi, Andrea
a58f3b10-5752-4fb8-8397-da25a4295164
Lobino, Mirko
3a4b0ec9-0578-4f2a-b4d6-c9f2b0aef18e
Matthews, Jonathan C.F.
27eacbd1-a28e-4cf2-a707-a77a79380a93
Politi, Alberto
cf75c0a8-d34d-4cbe-b9d5-e408c0edeeec
Neal, Chris R.
567a88eb-1cf4-415e-b67b-b4b4f916e41c
Ramponi, Roberta
2651461b-750a-43cc-96df-817f55fe26ad
Osellame, Roberto
b0ef5741-488b-42ae-934a-1a3eb424a203
O'Brien, Jeremy L.
03208a26-089b-4212-b691-87f26cff783c
Crespi, Andrea
a58f3b10-5752-4fb8-8397-da25a4295164
Lobino, Mirko
3a4b0ec9-0578-4f2a-b4d6-c9f2b0aef18e
Matthews, Jonathan C.F.
27eacbd1-a28e-4cf2-a707-a77a79380a93
Politi, Alberto
cf75c0a8-d34d-4cbe-b9d5-e408c0edeeec
Neal, Chris R.
567a88eb-1cf4-415e-b67b-b4b4f916e41c
Ramponi, Roberta
2651461b-750a-43cc-96df-817f55fe26ad
Osellame, Roberto
b0ef5741-488b-42ae-934a-1a3eb424a203
O'Brien, Jeremy L.
03208a26-089b-4212-b691-87f26cff783c

Crespi, Andrea, Lobino, Mirko, Matthews, Jonathan C.F., Politi, Alberto, Neal, Chris R., Ramponi, Roberta, Osellame, Roberto and O'Brien, Jeremy L. (2012) Measuring protein concentration with entangled photons. Applied Physics Letters, 100 (23), 233704-1-233704-5. (doi:10.1063/1.4724105).

Record type: Article

Abstract

Optical interferometry is amongst the most sensitive techniques for precision measurement. By increasing the light intensity, a more precise measurement can usually be made. However, if the sample is light sensitive entangled states can achieve the same precision with less exposure. This concept has been demonstrated in measurements of known optical components. Here, we use two-photon entangled states to measure the concentration of a blood protein in an aqueous buffer solution. We use an opto-fluidic device that couples a waveguide interferometer with a microfluidic channel. These results point the way to practical applications of quantum metrology to light-sensitive samples.

Full text not available from this repository.

More information

Accepted/In Press date: 11 May 2012
Published date: 5 June 2012
Organisations: Quantum, Light & Matter Group

Identifiers

Local EPrints ID: 377102
URI: http://eprints.soton.ac.uk/id/eprint/377102
ISSN: 0003-6951
PURE UUID: 26f049a2-41aa-4ee4-a0d3-bb35b6322e74
ORCID for Alberto Politi: ORCID iD orcid.org/0000-0002-3668-9474

Catalogue record

Date deposited: 26 May 2015 09:03
Last modified: 29 Oct 2019 01:37

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