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Evidence-based prevention and surgical treatment of necrotizing enterocolitis-a review of randomized controlled trials

Evidence-based prevention and surgical treatment of necrotizing enterocolitis-a review of randomized controlled trials
Evidence-based prevention and surgical treatment of necrotizing enterocolitis-a review of randomized controlled trials
Necrotizing enterocolitis remains a common cause of morbidity and mortality in the neonatal period. Despite many advances in the management of the critically ill neonate, the exact etiology, attempts at prevention and determining best treatment for NEC have been elusive. Unfortunately, the overall survival for this poorly understood and complex condition has not improved. NEC is a condition that can and should be studied with randomized prospective trials (RCTs). This chapter reviews the current evidence-based trials for this condition thus far performed
necrotizing enterocolitis, randomized controlled trials, NECSTEPS trial, NET trial, NEST trial, peritoneal drainage, laparotomy
1055-8586
117-121
Raval, Mehul V.
e4fb7328-a11b-42d5-9e8a-d83b110de882
Hall, Nigel J.
6919e8af-3890-42c1-98a7-c110791957cf
Pierro, Agostino
74bd6b37-4305-47fd-847d-c19a08718997
Moss, R. Lawrence
0dba9061-45c4-49fa-8742-714514c12cea
Raval, Mehul V.
e4fb7328-a11b-42d5-9e8a-d83b110de882
Hall, Nigel J.
6919e8af-3890-42c1-98a7-c110791957cf
Pierro, Agostino
74bd6b37-4305-47fd-847d-c19a08718997
Moss, R. Lawrence
0dba9061-45c4-49fa-8742-714514c12cea

Raval, Mehul V., Hall, Nigel J., Pierro, Agostino and Moss, R. Lawrence (2013) Evidence-based prevention and surgical treatment of necrotizing enterocolitis-a review of randomized controlled trials. Seminars in Pediatric Surgery, 22 (2), 117-121. (doi:10.1053/j.sempedsurg.2013.01.009). (PMID:23611616)

Record type: Article

Abstract

Necrotizing enterocolitis remains a common cause of morbidity and mortality in the neonatal period. Despite many advances in the management of the critically ill neonate, the exact etiology, attempts at prevention and determining best treatment for NEC have been elusive. Unfortunately, the overall survival for this poorly understood and complex condition has not improved. NEC is a condition that can and should be studied with randomized prospective trials (RCTs). This chapter reviews the current evidence-based trials for this condition thus far performed

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More information

Published date: May 2013
Keywords: necrotizing enterocolitis, randomized controlled trials, NECSTEPS trial, NET trial, NEST trial, peritoneal drainage, laparotomy
Organisations: Human Development & Health

Identifiers

Local EPrints ID: 378448
URI: http://eprints.soton.ac.uk/id/eprint/378448
ISSN: 1055-8586
PURE UUID: b935cf73-18ae-48cb-99f5-2e2d5cd0a36a
ORCID for Nigel J. Hall: ORCID iD orcid.org/0000-0001-8570-9374

Catalogue record

Date deposited: 06 Jul 2015 08:32
Last modified: 27 Apr 2022 01:55

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Contributors

Author: Mehul V. Raval
Author: Nigel J. Hall ORCID iD
Author: Agostino Pierro
Author: R. Lawrence Moss

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