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A review of conservative treatment of acute appendicitis

A review of conservative treatment of acute appendicitis
A review of conservative treatment of acute appendicitis
Appendicitis is a common condition in the pediatric population and appendectomy has been the traditional treatment. Both the urgency of the operation and the need for the appendectomy have recently been challenged. In children, this controversy focuses on operative management of perforated appendicitis and appendix abscesses. In adults, the debate has extended to management of nonperforated appendicitis. This review describes the evidence behind these challenges and updates a per-protocol meta-analysis of randomized controlled trials in adults. In the per-protocol meta-analysis, there was no difference between operative versus nonoperative management in failure of treatment. The complication rate was significantly lower in patients treated nonoperatively. However, in the nonoperative group, 10% of patients needed immediate surgery and 17% developed a recurrence during the 1-year follow-up. Overall, 73% of adults with suspected acute appendicitis may not need operative treatment. There are no data in the literature to support nonoperative treatment of acute appendicitis in children
acute appendicitis, appendectomy, pediatric population, conservative treatment
0939-7248
185-194
Svensson, J.F.
7e74ba60-5c88-4870-8710-1863c8e8459f
Hall, N.J.
6919e8af-3890-42c1-98a7-c110791957cf
Eaton, S.
77a21196-4388-442f-9306-3a013b8b1259
Pierro, A.
cef08d1c-bb0b-42ba-85ce-32d9a85c04a8
Wester, T.
549921ae-ebac-4f74-8883-f4db39f69051
Svensson, J.F.
7e74ba60-5c88-4870-8710-1863c8e8459f
Hall, N.J.
6919e8af-3890-42c1-98a7-c110791957cf
Eaton, S.
77a21196-4388-442f-9306-3a013b8b1259
Pierro, A.
cef08d1c-bb0b-42ba-85ce-32d9a85c04a8
Wester, T.
549921ae-ebac-4f74-8883-f4db39f69051

Svensson, J.F., Hall, N.J., Eaton, S., Pierro, A. and Wester, T. (2012) A review of conservative treatment of acute appendicitis. European Journal of Pediatric Surgery, 22 (3), 185-194. (doi:10.1055/s-0032-1320014). (PMID:22767171)

Record type: Article

Abstract

Appendicitis is a common condition in the pediatric population and appendectomy has been the traditional treatment. Both the urgency of the operation and the need for the appendectomy have recently been challenged. In children, this controversy focuses on operative management of perforated appendicitis and appendix abscesses. In adults, the debate has extended to management of nonperforated appendicitis. This review describes the evidence behind these challenges and updates a per-protocol meta-analysis of randomized controlled trials in adults. In the per-protocol meta-analysis, there was no difference between operative versus nonoperative management in failure of treatment. The complication rate was significantly lower in patients treated nonoperatively. However, in the nonoperative group, 10% of patients needed immediate surgery and 17% developed a recurrence during the 1-year follow-up. Overall, 73% of adults with suspected acute appendicitis may not need operative treatment. There are no data in the literature to support nonoperative treatment of acute appendicitis in children

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More information

Published date: June 2012
Keywords: acute appendicitis, appendectomy, pediatric population, conservative treatment
Organisations: Human Development & Health

Identifiers

Local EPrints ID: 378453
URI: http://eprints.soton.ac.uk/id/eprint/378453
ISSN: 0939-7248
PURE UUID: 75b0d4da-fa62-497e-8027-fb84720be52a
ORCID for N.J. Hall: ORCID iD orcid.org/0000-0001-8570-9374

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Date deposited: 03 Jul 2015 10:39
Last modified: 15 Mar 2024 03:38

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Contributors

Author: J.F. Svensson
Author: N.J. Hall ORCID iD
Author: S. Eaton
Author: A. Pierro
Author: T. Wester

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