Resection and primary anastomosis is a valid surgical option for infants with necrotizing enterocolitis who weigh less than 1000 g

Hall, N.J., Curry, J., Drake, D.P., Spitz, L., Kiely, E.M. and Pierro, A (2005) Resection and primary anastomosis is a valid surgical option for infants with necrotizing enterocolitis who weigh less than 1000 g. Archives of Surgery, 140 (12), 1149-1151. (PMID:16365234)

Abstract

Hypothesis: primary anastomosis following intestinal resection is a valid surgical option in the treatment of infants with necrotizing enterocolitis (NEC) who weigh less than 1000 g.

Design: retrospective case series.

Setting: tertiary neonatal surgery referral center.

Patients: all infants with confirmed NEC weighing less than 1000 g admitted to our intensive care unit over 4 years.

Intervention: or infants requiring laparotomy and intestinal resection, primary anastomosis was performed whenever the clinical condition permitted.

Main outcome measures: short- and long-term survival, length of intensive care unit stay, and complications.

Results: fifty-one infants with NEC who weighed less than 1000 g were admitted during the study period. Twelve infants underwent intestinal resection and primary anastomosis (median weight at surgery, 0.83 kg; range, 0.6-0.96 kg). One infant developed recurrent NEC, requiring further surgery, but there were no anastomotic leakages and no strictures. The median postoperative stay on our intensive care unit was 14 days (range, 2-49 days). All 12 infants survived their episode of acute NEC, and 8 are alive, with a median follow-up of 34.2 months (range, 4.7-48.4 months). Only 1 death was related to NEC. During the same period, 14 infants underwent intestinal resection and stoma formation. Ten survived the acute episode, and 6 are alive at a median follow-up of 24.0 months (range, 13.1-33.9 months). The median postoperative intensive care unit stay was 18 days (range, 2-74 days). Necrotizing enterocolitis–related complications occurred in 8 of these infants.

Conclusions: the outcome of infants with NEC who weigh less than 1000 g and undergo primary anastomosis is comparable to that of infants treated using alternative techniques. It is, therefore, a valid surgical option in selected infants. The mortality in this group of infants is high

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Contributors

Author: N.J. Hall

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