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A novel bioactive PEEK/HA composite with controlled 3D interconnected HA network

A novel bioactive PEEK/HA composite with controlled 3D interconnected HA network
A novel bioactive PEEK/HA composite with controlled 3D interconnected HA network
Polyetheretherketone (PEEK) is a high-performance thermoplastic biomaterial which is currently used in a variety of biomedical orthopaedic applications. It has comparable tensile and compressive strength to cortical bone with favourable biocompatibility. However, natural grade PEEK-OPTIMA has shown insufficient bioactivity and limited bone integration. Bioactive PEEK composites (e.g., PEEK/calcium phosphates or Bioglass) and porous PEEK have been used to improve bone-implant interface of PEEK-based devices, but the bioactive phase distribution or porosity control is poor. In this paper, a novel method is developed to fabricate a bioactive PEEK/hydroxyapatite (PEEK/HA) composite with a unique configuration in which the HA (bioactive phase) distribution is computer-controlled within a PEEK matrix. This novel process results in complete interconnectivity of the HA network within a composite material, representing a superior advantage over alternative forms of product. The technique combines extrusion freeforming, a type of additive manufacturing (AM), and compression moulding. Compression moulding parameters, including pressure, temperature, dwelling time, and loading method together with HA microstructure were optimized by experimentation for successful biocomposite production. PEEK/HA composites with a range of HA were produced using static pressure loading to minimise air entrapment within PEEK matrix. In addition, the technique can also be employed to produce porous PEEK structures with controlled pore size and distribution.
polyetheretherketone (PEEK), additive manufacturing (AM), bioactive PEEK/HA composite
2424-7723
66-76
Vaezi, Mohammad
828e14c1-3236-4153-8f69-3837233f48ed
Yang, Shoufeng
e0018adf-8123-4a54-b8dd-306c10ca48f1
Vaezi, Mohammad
828e14c1-3236-4153-8f69-3837233f48ed
Yang, Shoufeng
e0018adf-8123-4a54-b8dd-306c10ca48f1

Vaezi, Mohammad and Yang, Shoufeng (2015) A novel bioactive PEEK/HA composite with controlled 3D interconnected HA network. International Journal of Bioprinting, 1 (1), 66-76. (doi:10.18063/IJB.2015.01.004).

Record type: Article

Abstract

Polyetheretherketone (PEEK) is a high-performance thermoplastic biomaterial which is currently used in a variety of biomedical orthopaedic applications. It has comparable tensile and compressive strength to cortical bone with favourable biocompatibility. However, natural grade PEEK-OPTIMA has shown insufficient bioactivity and limited bone integration. Bioactive PEEK composites (e.g., PEEK/calcium phosphates or Bioglass) and porous PEEK have been used to improve bone-implant interface of PEEK-based devices, but the bioactive phase distribution or porosity control is poor. In this paper, a novel method is developed to fabricate a bioactive PEEK/hydroxyapatite (PEEK/HA) composite with a unique configuration in which the HA (bioactive phase) distribution is computer-controlled within a PEEK matrix. This novel process results in complete interconnectivity of the HA network within a composite material, representing a superior advantage over alternative forms of product. The technique combines extrusion freeforming, a type of additive manufacturing (AM), and compression moulding. Compression moulding parameters, including pressure, temperature, dwelling time, and loading method together with HA microstructure were optimized by experimentation for successful biocomposite production. PEEK/HA composites with a range of HA were produced using static pressure loading to minimise air entrapment within PEEK matrix. In addition, the technique can also be employed to produce porous PEEK structures with controlled pore size and distribution.

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More information

Accepted/In Press date: 17 June 2015
Published date: 2 July 2015
Keywords: polyetheretherketone (PEEK), additive manufacturing (AM), bioactive PEEK/HA composite
Organisations: Faculty of Engineering and the Environment

Identifiers

Local EPrints ID: 378685
URI: http://eprints.soton.ac.uk/id/eprint/378685
ISSN: 2424-7723
PURE UUID: 17e7206a-5ba2-44d1-b23a-156420412377
ORCID for Shoufeng Yang: ORCID iD orcid.org/0000-0002-3888-3211

Catalogue record

Date deposited: 09 Jul 2015 08:42
Last modified: 17 Dec 2019 01:41

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Contributors

Author: Mohammad Vaezi
Author: Shoufeng Yang ORCID iD

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