Approach to the child with hypercalcaemia
Approach to the child with hypercalcaemia
Hypercalcaemia is rare in children. In adulthood, the causes are most frequently malignancy and primary hyperparathyroidism. In children, however, the aetiologies are diverse and age specific, and many have an underlying genetic basis. Hypercalcaemia is a serious condition that frequently leads to end-organ damage. In order to provide the most appropriate treatment, a key part of the management pathway is to establish the correct diagnosis promptly. When considering a practical approach to hypercalcaemia in children, it is helpful to consider the causes of hypercalcaemia according to the accompanying levels of parathyroid hormone (PTH), indicating whether the causes are PTH dependent or PTH independent. This chapter reviews the recent advances in this area and presents a practical approach to the investigation and subsequent management of this condition
978-3-318-05466-8
101-118
Davies, Justin H.
9f18fcad-f488-4c72-ac23-c154995443a9
2015
Davies, Justin H.
9f18fcad-f488-4c72-ac23-c154995443a9
Davies, Justin H.
(2015)
Approach to the child with hypercalcaemia.
In,
Allgrove, J. and Shaw, N.J.
(eds.)
Calcium and Bone Disorders in Children and Adolescents.
(Endocrine Development, 28)
Basel, CH.
Karger, .
(doi:10.1159/000380998).
Record type:
Book Section
Abstract
Hypercalcaemia is rare in children. In adulthood, the causes are most frequently malignancy and primary hyperparathyroidism. In children, however, the aetiologies are diverse and age specific, and many have an underlying genetic basis. Hypercalcaemia is a serious condition that frequently leads to end-organ damage. In order to provide the most appropriate treatment, a key part of the management pathway is to establish the correct diagnosis promptly. When considering a practical approach to hypercalcaemia in children, it is helpful to consider the causes of hypercalcaemia according to the accompanying levels of parathyroid hormone (PTH), indicating whether the causes are PTH dependent or PTH independent. This chapter reviews the recent advances in this area and presents a practical approach to the investigation and subsequent management of this condition
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Published date: 2015
Organisations:
Human Development & Health
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Local EPrints ID: 378763
URI: http://eprints.soton.ac.uk/id/eprint/378763
ISBN: 978-3-318-05466-8
PURE UUID: 23e26b25-61f4-4b99-b4d2-e0f9ffee0f86
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Date deposited: 16 Jul 2015 09:18
Last modified: 14 Mar 2024 20:28
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Editor:
J. Allgrove
Editor:
N.J. Shaw
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