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Assessing the impact of including leaflets in the simulation of TAVI deployment in to a patient specific aortic root.

Assessing the impact of including leaflets in the simulation of TAVI deployment in to a patient specific aortic root.
Assessing the impact of including leaflets in the simulation of TAVI deployment in to a patient specific aortic root.
Computational simulation of transcatheter aortic valve implantation (TAVI) device deployment presents a significant challenge over and above similar simulations for percutaneous coronary intervention due to the presence of prosthetic leaflets. In light of the complexity of these leaflets, simulations have been performed to assess the effect of including the leaflets in a complete model of a balloon-expandable TAVI device when deployed in a patient-specific aortic root. Using an average model discrepancy metric, the average frame positions (with and without the leaflets) are shown to vary by 0.236% of the expanded frame diameter (26 mm). This relatively small discrepancy leads to the conclusion that for a broad range of replacement valve studies, including new frame configurations and designs, patient-specific assessment of apposition, paravalvular leakage and tissue stress, modelling of the prosthetic leaflets is likely to have a marginal effect on the results
TAVI, TAVR, leaflets, simulation, deploy and FEA
1025-5842
733-744
Bailey, Jonathan
c7291d98-c590-40dd-bfac-5e8065636c8f
Curzen, N.
70f3ea49-51b1-418f-8e56-8210aef1abf4
Bressloff, N.W.
4f531e64-dbb3-41e3-a5d3-e6a5a7a77c92
Bailey, Jonathan
c7291d98-c590-40dd-bfac-5e8065636c8f
Curzen, N.
70f3ea49-51b1-418f-8e56-8210aef1abf4
Bressloff, N.W.
4f531e64-dbb3-41e3-a5d3-e6a5a7a77c92

Bailey, Jonathan, Curzen, N. and Bressloff, N.W. (2016) Assessing the impact of including leaflets in the simulation of TAVI deployment in to a patient specific aortic root. Computer Methods in Biomechanics and Biomedical Engineering, 19 (7), 733-744. (doi:10.1080/10255842.2015.1058928).

Record type: Article

Abstract

Computational simulation of transcatheter aortic valve implantation (TAVI) device deployment presents a significant challenge over and above similar simulations for percutaneous coronary intervention due to the presence of prosthetic leaflets. In light of the complexity of these leaflets, simulations have been performed to assess the effect of including the leaflets in a complete model of a balloon-expandable TAVI device when deployed in a patient-specific aortic root. Using an average model discrepancy metric, the average frame positions (with and without the leaflets) are shown to vary by 0.236% of the expanded frame diameter (26 mm). This relatively small discrepancy leads to the conclusion that for a broad range of replacement valve studies, including new frame configurations and designs, patient-specific assessment of apposition, paravalvular leakage and tissue stress, modelling of the prosthetic leaflets is likely to have a marginal effect on the results

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Bailey_LeafletsTAVI_Comp_Meth_Biomech_BME_2015.pdf - Accepted Manuscript
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More information

Accepted/In Press date: 2 June 2015
e-pub ahead of print date: 21 July 2015
Published date: 2016
Keywords: TAVI, TAVR, leaflets, simulation, deploy and FEA
Organisations: Computational Engineering & Design Group

Identifiers

Local EPrints ID: 379546
URI: https://eprints.soton.ac.uk/id/eprint/379546
ISSN: 1025-5842
PURE UUID: 36ff5583-54d3-4094-8631-06328f79931e

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Date deposited: 28 Jul 2015 14:53
Last modified: 22 Nov 2017 17:31

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Contributors

Author: Jonathan Bailey
Author: N. Curzen
Author: N.W. Bressloff

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