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A 4-year follow-up of attention-deficit/hyperactivity disorder in a population sample

A 4-year follow-up of attention-deficit/hyperactivity disorder in a population sample
A 4-year follow-up of attention-deficit/hyperactivity disorder in a population sample
Background: Prior follow-up studies of attention-deficit/hyperactivity disorder (ADHD) ascertained ADHD cases in clinical samples mostly from North America but rarely from European countries. They have provided a good deal of information about the persistence of ADHD and its impairments, but the degree to which these results generalize to population samples and to other countries is not certain. Prior studies have also not assessed predictors of new-onset ADHD in youth without ADHD.

Method: At baseline, 7,912 of 18 million telephone numbers were randomly selected from throughout France from October 2, 2008, through December 11, 2008. Among 4,186 eligible families, 1,012 (24.2%) were successfully recruited at baseline, when a telephone interview was administered to all families about a child in the 6- to 12-year age range. Four years later, we attempted to recruit the entire sample to assess the persistence of ADHD and its impairments and the emergence of new associated conditions.

Results: 86.5% of the families assessed at baseline were followed-up (N = 875). Participants who were and were not interviewed at follow-up did not differ on any clinical or demographic features. At follow-up, the prevalence of full or subthreshold ADHD was 65.8% for ADHD participants and 9.8% for those not having ADHD at baseline. Among the children who were not diagnosed with ADHD at baseline, 3.4% were diagnosed with ADHD at follow-up. Both the persistence of ADHD and new onsets of ADHD were significantly predicted by several baseline clinical features and by having a family history of ADHD (all P values < .05).

Conclusions: We replicated prior predictors of ADHD’s persistence and provide new data about predictors of new ADHD onsets in the population. Our data about subthreshold ADHD support a dimensional conceptualization of the disorder and address the potential clinical utility of a subthreshold diagnostic category.
0160-6689
712-719
Lecendreux, Michel
51135545-1b33-4540-8ba9-1e8a1cc57173
Konofal, Eric
6328bf1a-74f1-4438-8c14-333ccc8931eb
Cortese, Samuele
53d4bf2c-4e0e-4c77-9385-218350560fdb
Faraone, Stephen V.
bd307516-e8db-4d38-b649-9d7d7caafe93
Lecendreux, Michel
51135545-1b33-4540-8ba9-1e8a1cc57173
Konofal, Eric
6328bf1a-74f1-4438-8c14-333ccc8931eb
Cortese, Samuele
53d4bf2c-4e0e-4c77-9385-218350560fdb
Faraone, Stephen V.
bd307516-e8db-4d38-b649-9d7d7caafe93

Lecendreux, Michel, Konofal, Eric, Cortese, Samuele and Faraone, Stephen V. (2015) A 4-year follow-up of attention-deficit/hyperactivity disorder in a population sample. The Journal of Clinical Psychiatry, 76 (6), 712-719. (doi:10.4088/JCP.14m09555).

Record type: Article

Abstract

Background: Prior follow-up studies of attention-deficit/hyperactivity disorder (ADHD) ascertained ADHD cases in clinical samples mostly from North America but rarely from European countries. They have provided a good deal of information about the persistence of ADHD and its impairments, but the degree to which these results generalize to population samples and to other countries is not certain. Prior studies have also not assessed predictors of new-onset ADHD in youth without ADHD.

Method: At baseline, 7,912 of 18 million telephone numbers were randomly selected from throughout France from October 2, 2008, through December 11, 2008. Among 4,186 eligible families, 1,012 (24.2%) were successfully recruited at baseline, when a telephone interview was administered to all families about a child in the 6- to 12-year age range. Four years later, we attempted to recruit the entire sample to assess the persistence of ADHD and its impairments and the emergence of new associated conditions.

Results: 86.5% of the families assessed at baseline were followed-up (N = 875). Participants who were and were not interviewed at follow-up did not differ on any clinical or demographic features. At follow-up, the prevalence of full or subthreshold ADHD was 65.8% for ADHD participants and 9.8% for those not having ADHD at baseline. Among the children who were not diagnosed with ADHD at baseline, 3.4% were diagnosed with ADHD at follow-up. Both the persistence of ADHD and new onsets of ADHD were significantly predicted by several baseline clinical features and by having a family history of ADHD (all P values < .05).

Conclusions: We replicated prior predictors of ADHD’s persistence and provide new data about predictors of new ADHD onsets in the population. Our data about subthreshold ADHD support a dimensional conceptualization of the disorder and address the potential clinical utility of a subthreshold diagnostic category.

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More information

Published date: 2015
Organisations: Clinical Neuroscience

Identifiers

Local EPrints ID: 380059
URI: http://eprints.soton.ac.uk/id/eprint/380059
ISSN: 0160-6689
PURE UUID: 3dd66376-3007-4c0c-8c86-695e984b4edf
ORCID for Samuele Cortese: ORCID iD orcid.org/0000-0001-5877-8075

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Date deposited: 19 Aug 2015 14:38
Last modified: 15 Mar 2024 03:52

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Contributors

Author: Michel Lecendreux
Author: Eric Konofal
Author: Samuele Cortese ORCID iD
Author: Stephen V. Faraone

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