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Physical rehabilitation for critical illness myopathy and neuropathy

Physical rehabilitation for critical illness myopathy and neuropathy
Physical rehabilitation for critical illness myopathy and neuropathy
BACKGROUND:
Intensive care unit (ICU) acquired or generalised weakness due to critical illness myopathy (CIM) and polyneuropathy (CIP) are major causes of chronically impaired motor function that can affect activities of daily living and quality of life. Physical rehabilitation of those affected might help to improve activities of daily living.

OBJECTIVES:
Our primary objective was to assess the effects of physical rehabilitation therapies and interventions for people with CIP and CIM in improving activities of daily living such as walking, bathing, dressing and eating. Secondary objectives were to assess effects on muscle strength and quality of life, and to assess adverse effects of physical rehabilitation.

SEARCH METHODS:
On 16 July 2014 we searched the Cochrane Neuromuscular Disease Group Specialized Register and on 14 July 2014 we searched CENTRAL, MEDLINE, EMBASE and CINAHL Plus. In July 2014, we searched the Physiotherapy Evidence Database (PEDro, http://www.pedro.org.au/) and three trials registries for ongoing trials and further data about included studies. There were no language restrictions. We also handsearched relevant conference proceedings and screened reference lists to identify further trials.

SELECTION CRITERIA:
We planned to include randomised controlled trials (RCTs), quasi-RCTs and randomised controlled cross-over trials of any rehabilitation intervention in people with acquired weakness syndrome due to CIP/CIM.

DATA COLLECTION AND ANALYSIS:
We would have extracted data, assessed the risk of bias and classified the quality of evidence for outcomes in duplicate, according to the standard procedures of The Cochrane Collaboration. Outcome data collection would have been for activities of daily living (for example, mobility, walking, transfers and self care). Secondary outcomes included muscle strength, quality of life and adverse events.

MAIN RESULTS:
The search strategy retrieved 3587 references. After examination of titles and abstracts, we retrieved the full text of 24 potentially relevant studies. None of these studies met the inclusion criteria of our review. No data were suitable to be included in a meta-analysis.

AUTHORS' CONCLUSIONS:
There are no published RCTs or quasi-RCTs that examine whether physical rehabilitation interventions improve activities of daily living for people with CIP and CIM. Large RCTs, which are feasible, need to be conducted to explore the role of physical rehabilitation interventions for people with CIP and CIM.
1465-1858
1-25
Mehrholz, Jan
9aa61e49-fa1f-44fa-a5ff-199019573421
Pohl, Marcus
54cc8eb0-baa3-453a-8617-4044123375d1
Kugler, Joachim
70cb7e7c-47a8-4e79-94ea-41bf41f886da
Burridge, Jane
0110e9ea-0884-4982-a003-cb6307f38f64
Mückel, Simone
9896111d-73ba-410b-9837-f32795046a47
Mehrholz, Jan
9aa61e49-fa1f-44fa-a5ff-199019573421
Pohl, Marcus
54cc8eb0-baa3-453a-8617-4044123375d1
Kugler, Joachim
70cb7e7c-47a8-4e79-94ea-41bf41f886da
Burridge, Jane
0110e9ea-0884-4982-a003-cb6307f38f64
Mückel, Simone
9896111d-73ba-410b-9837-f32795046a47

Mehrholz, Jan, Pohl, Marcus, Kugler, Joachim, Burridge, Jane and Mückel, Simone (2014) Physical rehabilitation for critical illness myopathy and neuropathy. The Cochrane Library, (1), 1-25, [CD010942]. (doi:10.1002/14651858.CD010942). (PMID:25737049)

Record type: Article

Abstract

BACKGROUND:
Intensive care unit (ICU) acquired or generalised weakness due to critical illness myopathy (CIM) and polyneuropathy (CIP) are major causes of chronically impaired motor function that can affect activities of daily living and quality of life. Physical rehabilitation of those affected might help to improve activities of daily living.

OBJECTIVES:
Our primary objective was to assess the effects of physical rehabilitation therapies and interventions for people with CIP and CIM in improving activities of daily living such as walking, bathing, dressing and eating. Secondary objectives were to assess effects on muscle strength and quality of life, and to assess adverse effects of physical rehabilitation.

SEARCH METHODS:
On 16 July 2014 we searched the Cochrane Neuromuscular Disease Group Specialized Register and on 14 July 2014 we searched CENTRAL, MEDLINE, EMBASE and CINAHL Plus. In July 2014, we searched the Physiotherapy Evidence Database (PEDro, http://www.pedro.org.au/) and three trials registries for ongoing trials and further data about included studies. There were no language restrictions. We also handsearched relevant conference proceedings and screened reference lists to identify further trials.

SELECTION CRITERIA:
We planned to include randomised controlled trials (RCTs), quasi-RCTs and randomised controlled cross-over trials of any rehabilitation intervention in people with acquired weakness syndrome due to CIP/CIM.

DATA COLLECTION AND ANALYSIS:
We would have extracted data, assessed the risk of bias and classified the quality of evidence for outcomes in duplicate, according to the standard procedures of The Cochrane Collaboration. Outcome data collection would have been for activities of daily living (for example, mobility, walking, transfers and self care). Secondary outcomes included muscle strength, quality of life and adverse events.

MAIN RESULTS:
The search strategy retrieved 3587 references. After examination of titles and abstracts, we retrieved the full text of 24 potentially relevant studies. None of these studies met the inclusion criteria of our review. No data were suitable to be included in a meta-analysis.

AUTHORS' CONCLUSIONS:
There are no published RCTs or quasi-RCTs that examine whether physical rehabilitation interventions improve activities of daily living for people with CIP and CIM. Large RCTs, which are feasible, need to be conducted to explore the role of physical rehabilitation interventions for people with CIP and CIM.

Text
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More information

Published date: 27 January 2014
Organisations: Faculty of Health Sciences

Identifiers

Local EPrints ID: 380393
URI: http://eprints.soton.ac.uk/id/eprint/380393
ISSN: 1465-1858
PURE UUID: bb72c6c5-9cec-470e-a4d5-1b3e2587dbc2
ORCID for Jane Burridge: ORCID iD orcid.org/0000-0003-3497-6725

Catalogue record

Date deposited: 14 Sep 2015 12:35
Last modified: 15 Mar 2024 02:57

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Contributors

Author: Jan Mehrholz
Author: Marcus Pohl
Author: Joachim Kugler
Author: Jane Burridge ORCID iD
Author: Simone Mückel

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