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Towards a high-precision, embedded system for versatile sensitive biosensing measurements

Towards a high-precision, embedded system for versatile sensitive biosensing measurements
Towards a high-precision, embedded system for versatile sensitive biosensing measurements
This paper demonstrates a versatile, high-Accuracy, data-Acquisition electronic platform for biosensing measurements, capable of collecting minute current and voltage input signals, stemming from various types of amperometric and potentiometric biosensors. The instrument is able to process the incoming analog signals in a digital manner and export them back to the user either as an amplified analog signal or in digital format through a USB 2.0 interface. The proposed system comprises off-The-shelf IC components and a commercially available FPGA-based DSP unit. The performance of the instrumentation platform has been tested initially by means of very small ideal current and voltage signals generated by precise electronic equipments and subsequently has been validated via proof-of-concept experiments with amperometric and potentiometric sensors. The results shown in this paper exhibit potential for integrating specific sections of the proposed instrumentation board with appropriate biosensors, towards developing affordable, yet reliable Point-Of-Care (POC) diagnostic tools for sensitive biochemical measurements.
Analog-To-Digital Conversion, Biosensing, Data-Acquisition, Embedded System, Nanoribbon TFT, PCB-Based Sensor, Switched Capacitor
IEEE
Papadimitriou, Konstantinos I.
c0535540-f862-41b1-9cf3-92b1f46a4145
Zeimpekis, Ioannis
a2c354ec-3891-497c-adac-89b3a5d96af0
Moschou, Despina
b5fef8ae-e4cb-4de5-8ade-1b5c807c74d3
Sun, Kai
b7c648a3-7be8-4613-9d4d-1bf937fb487b
Hu, Chunxiao
4892b566-6809-42a8-8285-1c1e93aac730
Ashburn, Peter
68cef6b7-205b-47aa-9efb-f1f09f5c1038
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Prodromakis, Themistoklis
d58c9c10-9d25-4d22-b155-06c8437acfbf
Papadimitriou, Konstantinos I.
c0535540-f862-41b1-9cf3-92b1f46a4145
Zeimpekis, Ioannis
a2c354ec-3891-497c-adac-89b3a5d96af0
Moschou, Despina
b5fef8ae-e4cb-4de5-8ade-1b5c807c74d3
Sun, Kai
b7c648a3-7be8-4613-9d4d-1bf937fb487b
Hu, Chunxiao
4892b566-6809-42a8-8285-1c1e93aac730
Ashburn, Peter
68cef6b7-205b-47aa-9efb-f1f09f5c1038
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Prodromakis, Themistoklis
d58c9c10-9d25-4d22-b155-06c8437acfbf

Papadimitriou, Konstantinos I., Zeimpekis, Ioannis, Moschou, Despina, Sun, Kai, Hu, Chunxiao, Ashburn, Peter, Morgan, Hywel and Prodromakis, Themistoklis (2015) Towards a high-precision, embedded system for versatile sensitive biosensing measurements. In Proceedings of the IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015. IEEE. 4 pp . (doi:10.1109/BioCAS.2015.7348432).

Record type: Conference or Workshop Item (Paper)

Abstract

This paper demonstrates a versatile, high-Accuracy, data-Acquisition electronic platform for biosensing measurements, capable of collecting minute current and voltage input signals, stemming from various types of amperometric and potentiometric biosensors. The instrument is able to process the incoming analog signals in a digital manner and export them back to the user either as an amplified analog signal or in digital format through a USB 2.0 interface. The proposed system comprises off-The-shelf IC components and a commercially available FPGA-based DSP unit. The performance of the instrumentation platform has been tested initially by means of very small ideal current and voltage signals generated by precise electronic equipments and subsequently has been validated via proof-of-concept experiments with amperometric and potentiometric sensors. The results shown in this paper exhibit potential for integrating specific sections of the proposed instrumentation board with appropriate biosensors, towards developing affordable, yet reliable Point-Of-Care (POC) diagnostic tools for sensitive biochemical measurements.

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More information

Published date: 7 December 2015
Additional Information: Funding Information: The authors acknowledge the financial support of the Engineering and Physical Sciences Research Council (EPSRC), EP/L020920/1 research grant. Publisher Copyright: © 2015 IEEE.
Venue - Dates: 11th IEEE Biomedical Circuits and Systems Conference, BioCAS 2015, , Atlanta, United States, 2015-10-22 - 2015-10-24
Keywords: Analog-To-Digital Conversion, Biosensing, Data-Acquisition, Embedded System, Nanoribbon TFT, PCB-Based Sensor, Switched Capacitor
Organisations: Nanoelectronics and Nanotechnology

Identifiers

Local EPrints ID: 380976
URI: http://eprints.soton.ac.uk/id/eprint/380976
PURE UUID: 6f999698-8f8b-421e-b545-15f74d87dcdd
ORCID for Ioannis Zeimpekis: ORCID iD orcid.org/0000-0002-7455-1599
ORCID for Hywel Morgan: ORCID iD orcid.org/0000-0003-4850-5676
ORCID for Themistoklis Prodromakis: ORCID iD orcid.org/0000-0002-6267-6909

Catalogue record

Date deposited: 21 Sep 2015 13:37
Last modified: 18 Mar 2024 03:18

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Contributors

Author: Konstantinos I. Papadimitriou
Author: Despina Moschou
Author: Kai Sun
Author: Chunxiao Hu
Author: Peter Ashburn
Author: Hywel Morgan ORCID iD
Author: Themistoklis Prodromakis ORCID iD

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