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Genetics: epigenetic mechanisms underlying type 2 diabetes mellitus

Genetics: epigenetic mechanisms underlying type 2 diabetes mellitus
Genetics: epigenetic mechanisms underlying type 2 diabetes mellitus
The aetiology of type 2 diabetes mellitus (T2DM) involves interactions between genetic, developmental and lifestyle environmental risk factors, which are partly influenced by epigenetic processes. Multhaup and colleagues have combined genome-wide analysis with analyses of an animal model of insulin resistance and tissues from individuals with obesity obtained before and after gastric bypass surgery to identify novel potential pathways that contribute to T2DM pathogenesis
1759-5029
261-262
Hanson, M.
1952fad1-abc7-4284-a0bc-a7eb31f70a3f
Godfrey, K.M.
0931701e-fe2c-44b5-8f0d-ec5c7477a6fd
Hanson, M.
1952fad1-abc7-4284-a0bc-a7eb31f70a3f
Godfrey, K.M.
0931701e-fe2c-44b5-8f0d-ec5c7477a6fd

Hanson, M. and Godfrey, K.M. (2015) Genetics: epigenetic mechanisms underlying type 2 diabetes mellitus. Nature Reviews Endocrinology, 11 (5), 261-262. (doi:10.1038/nrendo.2015.31.). (PMID:25752279)

Record type: Article

Abstract

The aetiology of type 2 diabetes mellitus (T2DM) involves interactions between genetic, developmental and lifestyle environmental risk factors, which are partly influenced by epigenetic processes. Multhaup and colleagues have combined genome-wide analysis with analyses of an animal model of insulin resistance and tissues from individuals with obesity obtained before and after gastric bypass surgery to identify novel potential pathways that contribute to T2DM pathogenesis

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Published date: 10 March 2015
Organisations: MRC Life-Course Epidemiology Unit

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Local EPrints ID: 381263
URI: http://eprints.soton.ac.uk/id/eprint/381263
DOI: doi:10.1038/nrendo.2015.31.
ISSN: 1759-5029
PURE UUID: da684ad4-3ade-49d0-a4a7-76f935735449
ORCID for M. Hanson: ORCID iD orcid.org/0000-0002-6907-613X
ORCID for K.M. Godfrey: ORCID iD orcid.org/0000-0002-4643-0618

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Date deposited: 02 Oct 2015 08:38
Last modified: 15 Mar 2024 03:07

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Contributors

Author: M. Hanson ORCID iD
Author: K.M. Godfrey ORCID iD

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