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Engineering fluidic delays in paper-based devices using laser direct-writing

Engineering fluidic delays in paper-based devices using laser direct-writing
Engineering fluidic delays in paper-based devices using laser direct-writing
We report the use of a new laser-based direct-write technique that allows programmable and timed fluid delivery in channels within a paper substrate which enables implementation of multi-step analytical assays. The technique is based on laser-induced photo-polymerisation, and through adjustment of the laser writing parameters such as the laser power and scan speed we can control the depth and/or the porosity of hydrophobic barriers which, when fabricated in the fluid path, produce controllable fluid delay. We have patterned these flow delaying barriers at pre-defined locations in the fluidic channels using either a continuous wave laser at 405nm, or a pulsed laser operating at 266nm. Using this delay patterning protocol we generated flow delays spanning from minutes to over an hour. Since the channels and flow delay barriers can be written via a common laser-writing process, this is a distinct improvement over other methods that require specialist operating environments, or custom-designed equipment. This technique can therefore be used for rapid fabrication of paper-based microfluidic devices that can perform single or multistep analytical assays.
1473-0197
4054-4061
He, P.J.W.
2e303166-6aa5-4a09-b22e-440d96a54a9f
Katis, I.N.
f92dfb8f-610d-4877-83f6-fd26a571df12
Eason, R.W.
e38684c3-d18c-41b9-a4aa-def67283b020
Sones, C.L.
9de9d8ee-d394-46a5-80b7-e341c0eed0a8
He, P.J.W.
2e303166-6aa5-4a09-b22e-440d96a54a9f
Katis, I.N.
f92dfb8f-610d-4877-83f6-fd26a571df12
Eason, R.W.
e38684c3-d18c-41b9-a4aa-def67283b020
Sones, C.L.
9de9d8ee-d394-46a5-80b7-e341c0eed0a8

He, P.J.W., Katis, I.N., Eason, R.W. and Sones, C.L. (2015) Engineering fluidic delays in paper-based devices using laser direct-writing. Lab on a Chip, 2015 (20), 4054-4061. (doi:10.1039/c5lc00590f).

Record type: Article

Abstract

We report the use of a new laser-based direct-write technique that allows programmable and timed fluid delivery in channels within a paper substrate which enables implementation of multi-step analytical assays. The technique is based on laser-induced photo-polymerisation, and through adjustment of the laser writing parameters such as the laser power and scan speed we can control the depth and/or the porosity of hydrophobic barriers which, when fabricated in the fluid path, produce controllable fluid delay. We have patterned these flow delaying barriers at pre-defined locations in the fluidic channels using either a continuous wave laser at 405nm, or a pulsed laser operating at 266nm. Using this delay patterning protocol we generated flow delays spanning from minutes to over an hour. Since the channels and flow delay barriers can be written via a common laser-writing process, this is a distinct improvement over other methods that require specialist operating environments, or custom-designed equipment. This technique can therefore be used for rapid fabrication of paper-based microfluidic devices that can perform single or multistep analytical assays.

Full text not available from this repository.

More information

Accepted/In Press date: 21 August 2015
e-pub ahead of print date: 25 August 2015
Published date: 21 October 2015
Organisations: Optoelectronics Research Centre

Identifiers

Local EPrints ID: 381447
URI: https://eprints.soton.ac.uk/id/eprint/381447
ISSN: 1473-0197
PURE UUID: b2bcc4d8-1dbf-4982-99d7-2368be63c569
ORCID for I.N. Katis: ORCID iD orcid.org/0000-0002-2016-557X
ORCID for R.W. Eason: ORCID iD orcid.org/0000-0001-9704-2204

Catalogue record

Date deposited: 10 Sep 2015 09:19
Last modified: 20 Jul 2019 01:25

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