Sexual differences in central arterial wave reflection are evident in prepubescent children
Sexual differences in central arterial wave reflection are evident in prepubescent children
OBJECTIVE: The objective of this study was to examine the influence of sex on central arterial wave reflection in healthy prepubescent children matched for body size and cardiorespiratory fitness.
METHODS: Fifty-five healthy children (9.8?±?1.0 years, 44% girls) were recruited. Cardiorespiratory fitness was assessed using a treadmill-based graded exercise test to volitional exhaustion. Pulse wave analysis was used to measure augmentation index (AIx) and central blood pressures.
RESULTS: The girls and boys were matched for age, body size and cardiorespiratory fitness. There were no significant differences between sexes for heart rate or central blood pressure parameters. Girls demonstrated a significantly greater AIx than the boys (8.9?±?9.3 vs. 1.9?±?10.8%, P?=?0.015, d?=?0.69).
CONCLUSION: Sexual differences in central arterial wave reflection exist prepubescence, independent of stature or cardiorespiratory fitness. Further study is required to elucidate the mechanism(s) explaining this phenomenon and to determine the influence of wave reflections on left ventricular mass during childhood.
arterial stiffness, central blood pressures, paediatric, pulse wave analysis, sex, wave reflections
304-307
Stoner, Lee
0f9dd581-205f-490d-8879-7ba7cfa51450
Faulkner, James
1bedc0f0-8fa4-4bf3-8e31-abd084b0c148
Westrupp, Nicole
7b5031cf-0116-4bb1-b56a-f4652eb72a55
Lambrick, Danielle
1deafa4b-acf3-4eff-83c9-f8274e47e993
February 2015
Stoner, Lee
0f9dd581-205f-490d-8879-7ba7cfa51450
Faulkner, James
1bedc0f0-8fa4-4bf3-8e31-abd084b0c148
Westrupp, Nicole
7b5031cf-0116-4bb1-b56a-f4652eb72a55
Lambrick, Danielle
1deafa4b-acf3-4eff-83c9-f8274e47e993
Stoner, Lee, Faulkner, James, Westrupp, Nicole and Lambrick, Danielle
(2015)
Sexual differences in central arterial wave reflection are evident in prepubescent children.
Journal of Hypertension, 33 (2), .
(doi:10.1097/HJH.0000000000000399).
(PMID:25304466)
Abstract
OBJECTIVE: The objective of this study was to examine the influence of sex on central arterial wave reflection in healthy prepubescent children matched for body size and cardiorespiratory fitness.
METHODS: Fifty-five healthy children (9.8?±?1.0 years, 44% girls) were recruited. Cardiorespiratory fitness was assessed using a treadmill-based graded exercise test to volitional exhaustion. Pulse wave analysis was used to measure augmentation index (AIx) and central blood pressures.
RESULTS: The girls and boys were matched for age, body size and cardiorespiratory fitness. There were no significant differences between sexes for heart rate or central blood pressure parameters. Girls demonstrated a significantly greater AIx than the boys (8.9?±?9.3 vs. 1.9?±?10.8%, P?=?0.015, d?=?0.69).
CONCLUSION: Sexual differences in central arterial wave reflection exist prepubescence, independent of stature or cardiorespiratory fitness. Further study is required to elucidate the mechanism(s) explaining this phenomenon and to determine the influence of wave reflections on left ventricular mass during childhood.
Text
Sexual differences in central arterial wave reflection are evident
- Version of Record
Restricted to Repository staff only
Request a copy
More information
Accepted/In Press date: 27 August 2014
Published date: February 2015
Keywords:
arterial stiffness, central blood pressures, paediatric, pulse wave analysis, sex, wave reflections
Organisations:
Bio-Behavioural Sciences
Identifiers
Local EPrints ID: 382071
URI: http://eprints.soton.ac.uk/id/eprint/382071
ISSN: 0263-6352
PURE UUID: d30a93f3-e2c3-4aa1-bf03-b0286f880c40
Catalogue record
Date deposited: 06 Oct 2015 11:57
Last modified: 15 Mar 2024 03:51
Export record
Altmetrics
Contributors
Author:
Lee Stoner
Author:
James Faulkner
Author:
Nicole Westrupp
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
