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Validation of oscillometric pulse wave analysis measurements in children

Validation of oscillometric pulse wave analysis measurements in children
Validation of oscillometric pulse wave analysis measurements in children
BACKGROUND:

Pulse wave analysis (PWA) has emerged as a noninvasive, valid, reliable, and widely used technique to investigate central blood pressures and systemic arterial wave reflection (augmentation index). The gold-standard technique is tonometry, but this technique can be challenging, especially when used on children. The purpose of this study was to validate oscillometric PWA for use in children.
METHODS:

Fifty-seven healthy children were recruited for participation. Central blood pressures and peripheral augmentation index (pAIx) were measured objectively using oscillometric (Pulsecor R7) and tonometric (SphygmaCor) devices. All measurements were made during the same visit under standardized conditions between the hours of 8 am and 10 am in the fasted state.
RESULTS:

Tonometric measurements were unsuccessful on 1 child. Comparisons were made on 56 children (mean age = 9.8±1.0 y; 57% male). A very strong relationship was found between devices for central systolic (r = 0.94; P < 0.001), diastolic (r = 0.99; P < 0.001) and mean (r = 0.96; P < 0.001) blood pressures. However, Bland-Altman analysis indicated a bias toward greater systolic blood pressures with the oscillometric monitor (mean difference = 4.5mm Hg; 95% confidence interval (CI) = -5.16 to -3.89). A good relationship was found for pAIx (r = 0.71; P < 0.001); the mean difference between devices was -1.70% (95% CI = -4.47% to 1.08%), which is not significantly different from zero.
CONCLUSIONS:

Findings from this study suggest that oscillometric PWA provides valid measures of central blood pressure and arterial wave reflection in children aged 8-10 years.
0895-7061
865-872
Stoner, L.
3ddab4db-e142-4bf1-bb1c-b6d685933aa2
Lambrick, D. M.
1deafa4b-acf3-4eff-83c9-f8274e47e993
Westrupp, N.
9c069ec9-e6e6-4bce-bec7-6ffdb8971290
Young, J.
1b5515d8-ab56-4eda-a35f-5bc042d034f5
Faulkner, J.
16a65aac-bf2d-45ef-80c5-d70fbc3d7bfc
Stoner, L.
3ddab4db-e142-4bf1-bb1c-b6d685933aa2
Lambrick, D. M.
1deafa4b-acf3-4eff-83c9-f8274e47e993
Westrupp, N.
9c069ec9-e6e6-4bce-bec7-6ffdb8971290
Young, J.
1b5515d8-ab56-4eda-a35f-5bc042d034f5
Faulkner, J.
16a65aac-bf2d-45ef-80c5-d70fbc3d7bfc

Stoner, L., Lambrick, D. M., Westrupp, N., Young, J. and Faulkner, J. (2014) Validation of oscillometric pulse wave analysis measurements in children. American Journal of Hypertension, 27 (6), 865-872. (doi:10.1093/ajh/hpt243). (PMID:24390294)

Record type: Article

Abstract

BACKGROUND:

Pulse wave analysis (PWA) has emerged as a noninvasive, valid, reliable, and widely used technique to investigate central blood pressures and systemic arterial wave reflection (augmentation index). The gold-standard technique is tonometry, but this technique can be challenging, especially when used on children. The purpose of this study was to validate oscillometric PWA for use in children.
METHODS:

Fifty-seven healthy children were recruited for participation. Central blood pressures and peripheral augmentation index (pAIx) were measured objectively using oscillometric (Pulsecor R7) and tonometric (SphygmaCor) devices. All measurements were made during the same visit under standardized conditions between the hours of 8 am and 10 am in the fasted state.
RESULTS:

Tonometric measurements were unsuccessful on 1 child. Comparisons were made on 56 children (mean age = 9.8±1.0 y; 57% male). A very strong relationship was found between devices for central systolic (r = 0.94; P < 0.001), diastolic (r = 0.99; P < 0.001) and mean (r = 0.96; P < 0.001) blood pressures. However, Bland-Altman analysis indicated a bias toward greater systolic blood pressures with the oscillometric monitor (mean difference = 4.5mm Hg; 95% confidence interval (CI) = -5.16 to -3.89). A good relationship was found for pAIx (r = 0.71; P < 0.001); the mean difference between devices was -1.70% (95% CI = -4.47% to 1.08%), which is not significantly different from zero.
CONCLUSIONS:

Findings from this study suggest that oscillometric PWA provides valid measures of central blood pressure and arterial wave reflection in children aged 8-10 years.

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More information

e-pub ahead of print date: 3 January 2014
Published date: June 2014
Organisations: Faculty of Health Sciences

Identifiers

Local EPrints ID: 382254
URI: http://eprints.soton.ac.uk/id/eprint/382254
ISSN: 0895-7061
PURE UUID: b3506094-c9b7-4514-aa6e-fb5213937cb2
ORCID for D. M. Lambrick: ORCID iD orcid.org/0000-0002-0325-6015

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Date deposited: 01 Oct 2015 09:32
Last modified: 15 Mar 2024 03:51

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Contributors

Author: L. Stoner
Author: D. M. Lambrick ORCID iD
Author: N. Westrupp
Author: J. Young
Author: J. Faulkner

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