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Pre-adolescent cardio-metabolic associations and correlates: PACMAC methodology and study protocol

Pre-adolescent cardio-metabolic associations and correlates: PACMAC methodology and study protocol
Pre-adolescent cardio-metabolic associations and correlates: PACMAC methodology and study protocol
Introduction Although cardiovascular disease is typically associated with middle or old age, the atherosclerotic process often initiates early in childhood. The process of atherosclerosis appears to be occurring at an increasing rate, even in pre-adolescents, and has been linked to the childhood obesity epidemic. This study will investigate the relationships between obesity, lifestyle behaviours and cardiometabolic health in pre-pubescent children aged 8–10?years, and investigates whether there are differences in the correlates of cardiometabolic health between M?ori and Caucasian children. Details of the methodological aspects of recruitment, inclusion/exclusion criteria, assessments, statistical analyses, dissemination of findings and anticipated impact are described.

Methods and analysis Phase 1: a cross-sectional study design will be used to investigate relationships between obesity, lifestyle behaviours (nutrition, physical activity/fitness, sleep behaviour, psychosocial influences) and cardiometabolic health in a sample of 400 pre-pubescent (8–10?years old) children. Phase 2: in a subgroup (50 Caucasian, 50 M?ori children), additional measurements of cardiometabolic health and lifestyle behaviours will be obtained to provide objective and detailed data. General linear models and logistic regression will be used to investigate the strongest correlate of (1) fatness; (2) physical activity; (3) nutritional behaviours and (4) cardiometabolic health.

Ethics and dissemination Ethical approval will be obtained from the New Zealand Health and Disabilities Ethics Committee. The findings from this study will elucidate targets for decreasing obesity and improving cardiometabolic health among preadolescent children in New Zealand. The aim is to ensure an immediate impact by disseminating these findings in an applicable manner via popular media and traditional academic forums. Most importantly, results from the study will be disseminated to participating schools and relevant M?ori health entities.
e005815
Castro, N.
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Faulkner, J.
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Skidmore, P.
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Williams, M.
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Lambrick, D. M.
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Signal, L.
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Thunders, M.
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Muller, D.
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Lark, S.
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Hamlin, M.
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Lane, A. M.
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Kingi, T. K.
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Stoner, L.
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Castro, N.
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Faulkner, J.
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Skidmore, P.
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Williams, M.
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Lambrick, D. M.
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Signal, L.
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Thunders, M.
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Muller, D.
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Lark, S.
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Hamlin, M.
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Lane, A. M.
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Kingi, T. K.
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Stoner, L.
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Castro, N., Faulkner, J., Skidmore, P., Williams, M., Lambrick, D. M., Signal, L., Thunders, M., Muller, D., Lark, S., Hamlin, M., Lane, A. M., Kingi, T. K. and Stoner, L. (2014) Pre-adolescent cardio-metabolic associations and correlates: PACMAC methodology and study protocol. BMJ Open, 4 (9), e005815. (doi:10.1136/bmjopen-2014-005815).

Record type: Article

Abstract

Introduction Although cardiovascular disease is typically associated with middle or old age, the atherosclerotic process often initiates early in childhood. The process of atherosclerosis appears to be occurring at an increasing rate, even in pre-adolescents, and has been linked to the childhood obesity epidemic. This study will investigate the relationships between obesity, lifestyle behaviours and cardiometabolic health in pre-pubescent children aged 8–10?years, and investigates whether there are differences in the correlates of cardiometabolic health between M?ori and Caucasian children. Details of the methodological aspects of recruitment, inclusion/exclusion criteria, assessments, statistical analyses, dissemination of findings and anticipated impact are described.

Methods and analysis Phase 1: a cross-sectional study design will be used to investigate relationships between obesity, lifestyle behaviours (nutrition, physical activity/fitness, sleep behaviour, psychosocial influences) and cardiometabolic health in a sample of 400 pre-pubescent (8–10?years old) children. Phase 2: in a subgroup (50 Caucasian, 50 M?ori children), additional measurements of cardiometabolic health and lifestyle behaviours will be obtained to provide objective and detailed data. General linear models and logistic regression will be used to investigate the strongest correlate of (1) fatness; (2) physical activity; (3) nutritional behaviours and (4) cardiometabolic health.

Ethics and dissemination Ethical approval will be obtained from the New Zealand Health and Disabilities Ethics Committee. The findings from this study will elucidate targets for decreasing obesity and improving cardiometabolic health among preadolescent children in New Zealand. The aim is to ensure an immediate impact by disseminating these findings in an applicable manner via popular media and traditional academic forums. Most importantly, results from the study will be disseminated to participating schools and relevant M?ori health entities.

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Accepted/In Press date: 27 August 2014
Published date: 18 September 2014
Organisations: Faculty of Health Sciences

Identifiers

Local EPrints ID: 382282
URI: http://eprints.soton.ac.uk/id/eprint/382282
PURE UUID: d825597d-d6ad-4d31-8d18-37ef5278778b
ORCID for D. M. Lambrick: ORCID iD orcid.org/0000-0002-0325-6015

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Date deposited: 01 Oct 2015 13:12
Last modified: 15 Mar 2024 03:51

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Contributors

Author: N. Castro
Author: J. Faulkner
Author: P. Skidmore
Author: M. Williams
Author: D. M. Lambrick ORCID iD
Author: L. Signal
Author: M. Thunders
Author: D. Muller
Author: S. Lark
Author: M. Hamlin
Author: A. M. Lane
Author: T. K. Kingi
Author: L. Stoner

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