The cost-effectiveness of second-eye cataract surgery in UK
The cost-effectiveness of second-eye cataract surgery in UK
Background: elective cataract surgery is the most commonly performed surgical procedure in developed countries. However, it is unclear whether cataract surgery on the second eye provides enough incremental benefit to be considered cost-effective. This study conducted a cost-effectiveness analysis of second-eye cataract surgery in the UK.
Design: a cost-effectiveness analysis.
Methods: a decision-analytical model was developed to estimate the cost-effectiveness of second-eye cataract surgery, based on a comprehensive epidemiological and economic review to develop the parameters for the model. The model followed the clinical pathway of cohorts of patients receiving second-eye cataract surgery and included costs and health benefits associated with post-surgical complications.
Results: in the model, second-eye surgery generated 0.68 additional quality-adjusted life years (QALY) with an incremental cost-effectiveness ratio of £1,964 per QALY gained. In sensitivity analyses, model results were most sensitive to changes in the health-related quality of life (HRQoL) gain associated with second-eye surgery, but otherwise robust to changes in parameter values. The probability that second-eye surgery is cost-effective at willingness to pay thresholds of £10,000 and £20,000 was 100%.
Conclusion: second-eye cataract surgery is generally cost-effective based on the best available data and under most assumptions. However, there are only a small number of clinical trials for second-eye cataract surgery, and these have not been conducted in recent years.
cataract, cost-effectiveness, second-eye surgery, older people
1026-1031
Cooper, Keith
ea064f58-d71d-404a-bcf3-49d243b8825b
Shepherd, Jonathan
dfbca97a-9307-4eee-bdf7-e27bcb02bc67
Frampton, Geoff
26c6163c-3428-45b8-b8b9-92091ff6c69f
Harris, Petra
0e15de29-ece4-43e6-9861-4e20bcee5acd
Lotery, Andrew
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514
November 2015
Cooper, Keith
ea064f58-d71d-404a-bcf3-49d243b8825b
Shepherd, Jonathan
dfbca97a-9307-4eee-bdf7-e27bcb02bc67
Frampton, Geoff
26c6163c-3428-45b8-b8b9-92091ff6c69f
Harris, Petra
0e15de29-ece4-43e6-9861-4e20bcee5acd
Lotery, Andrew
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514
Cooper, Keith, Shepherd, Jonathan, Frampton, Geoff, Harris, Petra and Lotery, Andrew
(2015)
The cost-effectiveness of second-eye cataract surgery in UK.
Age and Ageing, 44 (6), .
(doi:10.1093/ageing/afv126).
(PMID:26410365)
Abstract
Background: elective cataract surgery is the most commonly performed surgical procedure in developed countries. However, it is unclear whether cataract surgery on the second eye provides enough incremental benefit to be considered cost-effective. This study conducted a cost-effectiveness analysis of second-eye cataract surgery in the UK.
Design: a cost-effectiveness analysis.
Methods: a decision-analytical model was developed to estimate the cost-effectiveness of second-eye cataract surgery, based on a comprehensive epidemiological and economic review to develop the parameters for the model. The model followed the clinical pathway of cohorts of patients receiving second-eye cataract surgery and included costs and health benefits associated with post-surgical complications.
Results: in the model, second-eye surgery generated 0.68 additional quality-adjusted life years (QALY) with an incremental cost-effectiveness ratio of £1,964 per QALY gained. In sensitivity analyses, model results were most sensitive to changes in the health-related quality of life (HRQoL) gain associated with second-eye surgery, but otherwise robust to changes in parameter values. The probability that second-eye surgery is cost-effective at willingness to pay thresholds of £10,000 and £20,000 was 100%.
Conclusion: second-eye cataract surgery is generally cost-effective based on the best available data and under most assumptions. However, there are only a small number of clinical trials for second-eye cataract surgery, and these have not been conducted in recent years.
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More information
Accepted/In Press date: 27 July 2015
e-pub ahead of print date: 26 September 2015
Published date: November 2015
Keywords:
cataract, cost-effectiveness, second-eye surgery, older people
Organisations:
Primary Care & Population Sciences
Identifiers
Local EPrints ID: 382314
URI: http://eprints.soton.ac.uk/id/eprint/382314
ISSN: 0002-0729
PURE UUID: eb1d5858-46b5-4b0d-a928-57d6443e2748
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Date deposited: 29 Oct 2015 09:07
Last modified: 15 Mar 2024 03:16
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Author:
Petra Harris
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