Elkington, P. and Zumla, A. (2015) Update in Mycobacterium tuberculosis lung disease 2014. American Journal of Respiratory and Critical Care Medicine, 192 (7), 793-798. (doi:10.1164/rccm.201505-1009UP). (PMID:26426784)
Abstract
The global tuberculosis (TB) pandemic continues despite intensive TB control and research efforts. Research articles related on Mycobacterium tuberculosis (M.tb) infection published in the Journal focused on five main areas: basic science, evaluation of novel diagnostics, epidemiology, transmission, and clinical trials. These range from exciting developments in new compounds to treat multidrug-resistant (MDR)-TB to major disappointments from clinical trials evaluating new treatment-shortening regimens and vaccine efficacy studies. We review these publications and discuss developments and approaches that may maximize improved TB management.
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