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Diagnostic methods in primary ciliary dyskinesia: Mini-symposium: Primary Ciliary Dyskinesia

Diagnostic methods in primary ciliary dyskinesia: Mini-symposium: Primary Ciliary Dyskinesia
Diagnostic methods in primary ciliary dyskinesia: Mini-symposium: Primary Ciliary Dyskinesia
Diagnosing primary ciliary dyskinesia is difficult. With no reference standard, a combination of tests is needed; most tests require expensive equipment and specialist scientists. We review the advances in diagnostic testing over the past hundred years, with emphasis on recent advances. We particularly focus on use of high-speed video analysis, transmission electron microscopy, nasal nitric oxide and genetic testing. We discuss the international efforts that are in place to advance the evidence base for diagnostic tests.
primary ciliary dyskinesia, diagnosis, high speed video analysis, electron microscopy, genetics, nitric oxide
1526-0550
1-10
Lucas, Jane S.
5cb3546c-87b2-4e59-af48-402076e25313
Paff, Tamara
53db2d24-d748-4cfd-8f68-51ef4d60ab5a
Goggin, Patricia
c2d225c4-b84d-4ead-a433-320057cb5fa9
Haarman, Eric
953b1ca1-3218-435c-9a0e-32e7b2d95798
Lucas, Jane S.
5cb3546c-87b2-4e59-af48-402076e25313
Paff, Tamara
53db2d24-d748-4cfd-8f68-51ef4d60ab5a
Goggin, Patricia
c2d225c4-b84d-4ead-a433-320057cb5fa9
Haarman, Eric
953b1ca1-3218-435c-9a0e-32e7b2d95798

Lucas, Jane S., Paff, Tamara, Goggin, Patricia and Haarman, Eric (2017) Diagnostic methods in primary ciliary dyskinesia: Mini-symposium: Primary Ciliary Dyskinesia. Paediatric Respiratory Reviews, 1-10. (doi:10.1016/j.prrv.2015.07.017). (PMID:26362507)

Record type: Article

Abstract

Diagnosing primary ciliary dyskinesia is difficult. With no reference standard, a combination of tests is needed; most tests require expensive equipment and specialist scientists. We review the advances in diagnostic testing over the past hundred years, with emphasis on recent advances. We particularly focus on use of high-speed video analysis, transmission electron microscopy, nasal nitric oxide and genetic testing. We discuss the international efforts that are in place to advance the evidence base for diagnostic tests.

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2015 PCD Diagnosis Paed Resp Rev_YPRRV_1069.pdf - Other
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2015 PCD Diagnosis Paed Resp Rev_Lucas Diagnostic Review Paed Resp Rev 2015.pdf - Other
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More information

Accepted/In Press date: 30 July 2015
e-pub ahead of print date: 19 August 2015
Published date: March 2017
Keywords: primary ciliary dyskinesia, diagnosis, high speed video analysis, electron microscopy, genetics, nitric oxide
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 383073
URI: https://eprints.soton.ac.uk/id/eprint/383073
ISSN: 1526-0550
PURE UUID: 005c96b8-1eee-4aee-a46f-f284c9ca613b

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Date deposited: 22 Oct 2015 10:45
Last modified: 09 Dec 2019 19:49

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