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Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia

Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia
Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia
The epidemiology of non-typeable Haemophilus influenzae (NTHi) remains poorly understood. We therefore sought to determine the genetic relationship of 25 NTHi isolated from various states in Malaysia using multilocus sequence typing (MLST). The majority of isolates were obtained from sputum. There were 24 novel sequence types (STs). Eight isolates were single-locus variants, the remainder being singletons. Clustering was not based on clinical site of isolation or geographical origin. Despite the limited number of isolates examined in this study, we demonstrate that NTHi isolates in Malaysia are diverse and warrant further investigation.
non-typeable haemophilus influenzae, phylogenetic, malaysia, MLST
1567-1348
240-243
Mohd-Zain, Zaini
c0c2249c-fa0e-4907-a0e1-944d6abab8bc
Kamsani, Nurul H.
fa998772-5e62-4163-9a20-9baf3877b982
Ahmad, Norazah
25d647c5-1ab9-4d25-9ece-17e1cb726e79
Clarke, Stuart C.
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17
Mohd-Zain, Zaini
c0c2249c-fa0e-4907-a0e1-944d6abab8bc
Kamsani, Nurul H.
fa998772-5e62-4163-9a20-9baf3877b982
Ahmad, Norazah
25d647c5-1ab9-4d25-9ece-17e1cb726e79
Clarke, Stuart C.
f7d7f7a2-4b1f-4b36-883a-0f967e73fb17

Mohd-Zain, Zaini, Kamsani, Nurul H., Ahmad, Norazah and Clarke, Stuart C. (2015) Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia. Infection, Genetics and Evolution, 36, 240-243. (doi:10.1016/j.meegid.2015.09.017). (PMID:26394107)

Record type: Article

Abstract

The epidemiology of non-typeable Haemophilus influenzae (NTHi) remains poorly understood. We therefore sought to determine the genetic relationship of 25 NTHi isolated from various states in Malaysia using multilocus sequence typing (MLST). The majority of isolates were obtained from sputum. There were 24 novel sequence types (STs). Eight isolates were single-locus variants, the remainder being singletons. Clustering was not based on clinical site of isolation or geographical origin. Despite the limited number of isolates examined in this study, we demonstrate that NTHi isolates in Malaysia are diverse and warrant further investigation.

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Accepted/In Press date: 17 September 2015
e-pub ahead of print date: 21 September 2015
Published date: December 2015
Keywords: non-typeable haemophilus influenzae, phylogenetic, malaysia, MLST
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 383186
URI: https://eprints.soton.ac.uk/id/eprint/383186
ISSN: 1567-1348
PURE UUID: 270cd705-a844-4aab-9664-68041ab0e40b
ORCID for Stuart C. Clarke: ORCID iD orcid.org/0000-0002-7009-1548

Catalogue record

Date deposited: 22 Oct 2015 13:41
Last modified: 06 Jun 2018 12:40

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