Hennis, Philip J., O'Doherty, Alasdair F., Levett, Denny Z.H., Grocott, Michael P.W. and Montgomery, Hugh M.
Genetic factors associated with exercise performance in atmospheric hypoxia
Sports Medicine, 45, (5), . (doi:10.1007/s40279-015-0309-8). (PMID:25682119).
The small number of articles identified in the current review and the limited number of polymorphisms studied in total highlights that the influence of genetic factors on exercise performance in hypoxia has not been studied in depth, which precludes firm conclusions being drawn. Support for the association between the ACE-I allele and improved high-altitude performance was the strongest, with three studies identifying a relationship. Analysis of study quality highlights the need for future studies in this field to improve the conduct and reporting of genetic association studies.
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