Sanborn, Matthew R., Edsell, Mark E., Kim, Meeri N., Mesquita, Rickson, Putt, Mary E., Imray, Chris, Yow, Heng, Wilson, Mark H., Yodh, Arjun G., Grocott, Mike and Martin, Daniel S.
Cerebral hemodynamics at altitude: effects of hyperventilation and acclimatization on cerebral blood flow and oxygenation
Wilderness and Environmental Medicine, 26, (2), . (doi:10.1016/j.wem.2014.10.001). (PMID:25797567).
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An intensification of the normal cerebral hypocapnic vasoconstrictive response occurred after partial acclimatization in the setting of divergent peripheral and cerebral oxygenation. This may help explain why hyperventilation fails to improve cerebral oxygenation after partial acclimatization as it does after initial ascent. The use of DCS is feasible at altitude and provides a direct measure of CBF indices with high temporal resolution.
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