Kuchenbaecker, Karoline B, Neuhausen, Susan L and Robson, Mark et al. (2014) Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research, 16 (6), 3416. (doi:10.1186/s13058-014-0492-9). (PMID:25919761)
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Abstract
Differences in associations of common BC susceptibility alleles between BRCA1 and BRCA2 carriers and the general population are explained to a large extent by differences in the prevalence of ER-positive and ER-negative tumors. Estimates of the risks associated with these variants based on population-based studies are likely to be applicable to mutation carriers after taking ER status into account, which has implications for risk prediction.
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Accepted/In Press date: 2 December 2014
Published date: 31 December 2014
Organisations:
Cancer Sciences
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Local EPrints ID: 384319
URI: http://eprints.soton.ac.uk/id/eprint/384319
PURE UUID: 23000979-dc0e-468d-9563-1c520a7b4834
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Date deposited: 22 Dec 2015 10:32
Last modified: 15 Mar 2024 02:40
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Author:
Karoline B Kuchenbaecker
Author:
Susan L Neuhausen
Author:
Mark Robson
Author:
Daniel Barrowdale
Author:
Lesley McGuffog
Author:
Anna Marie Mulligan
Author:
Irene L Andrulis
Author:
Amanda B Spurdle
Author:
Marjanka K Schmidt
Author:
Rita K Schmutzler
Author:
Christoph Engel
Author:
Barbara Wappenschmidt
Author:
Heli Nevanlinna
Author:
Mads Thomassen
Author:
Melissa Southey
Author:
Paolo Radice
Author:
Susan J Ramus
Author:
Susan M Domchek
Author:
Katherine L Nathanson
Author:
Andrew Lee
Author:
Sue Healey
Author:
Robert L Nussbaum
Author:
Timothy R Rebbeck
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Banu K Arun
Author:
Paul James
Author:
Beth Y Karlan
Author:
Jenny Lester
Author:
Ilana Cass
Author:
Mary Beth Terry
Author:
Mary B Daly
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David E Goldgar
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Saundra S Buys
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Ramunas Janavicius
Author:
Laima Tihomirova
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Nadine Tung
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Cecilia M Dorfling
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Elizabeth J van Rensburg
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Linda Steele
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Thomas v O Hansen
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Bent Ejlertsen
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Anne-Marie Gerdes
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Finn C Nielsen
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Joe Dennis
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Julie Cunningham
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Steven Hart
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Susan Slager
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Javier Benitez
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Rosemarie Davidson
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Kerstin Rhiem
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Alfons Meindl
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