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Laser-induced photo-polymerisation for creation of paper-based fluidic devices

Laser-induced photo-polymerisation for creation of paper-based fluidic devices
Laser-induced photo-polymerisation for creation of paper-based fluidic devices
Paper-based microfluidics is a rapidly progressing inter-disciplinary technology driven by the need for low-cost alternatives to conventional point-of-care diagnostic tools. For transport of reagents/analytes, such devices often consist of interconnected hydrophilic fluid-flow channels that are demarcated by hydrophobic barrier walls that extend through the thickness of the paper. Here, we present a laser-based fabrication procedure that uses polymerisation of a photopolymer to produce the required fluidic channels in paper. Experimental results showed that the structures successfully guide the flow of fluids and allow containment of fluids in wells, and hence the technique is suitable for fabrication of paper-based microfluidic devices. The minimum width for the hydrophobic barriers that successfully prevented fluid leakage was ~120 µm and the minimum width for the fluidic channels that can be formed was ~80 µm, the smallest reported so far for paper-based fluidic patterns.
1473-0197
4567-4574
Sones, C.L.
9de9d8ee-d394-46a5-80b7-e341c0eed0a8
Katis, I.N.
f92dfb8f-610d-4877-83f6-fd26a571df12
He, P.J.W.
2e303166-6aa5-4a09-b22e-440d96a54a9f
Mills, B.
05f1886e-96ef-420f-b856-4115f4ab36d0
Namiq, M.F.
4c1f64fc-8a98-496c-bd0a-63a6a92cbe84
Shardlow, P.
9ca17301-8ae7-4307-8bb9-371df461520c
Ibsen, M.
22e58138-5ce9-4bed-87e1-735c91f8f3b9
Eason, R.W.
e38684c3-d18c-41b9-a4aa-def67283b020
Sones, C.L.
9de9d8ee-d394-46a5-80b7-e341c0eed0a8
Katis, I.N.
f92dfb8f-610d-4877-83f6-fd26a571df12
He, P.J.W.
2e303166-6aa5-4a09-b22e-440d96a54a9f
Mills, B.
05f1886e-96ef-420f-b856-4115f4ab36d0
Namiq, M.F.
4c1f64fc-8a98-496c-bd0a-63a6a92cbe84
Shardlow, P.
9ca17301-8ae7-4307-8bb9-371df461520c
Ibsen, M.
22e58138-5ce9-4bed-87e1-735c91f8f3b9
Eason, R.W.
e38684c3-d18c-41b9-a4aa-def67283b020

Sones, C.L., Katis, I.N., He, P.J.W., Mills, B., Namiq, M.F., Shardlow, P., Ibsen, M. and Eason, R.W. (2014) Laser-induced photo-polymerisation for creation of paper-based fluidic devices. Lab on a Chip, 14 (23), 4567-4574. (doi:10.1039/C4LC00850B).

Record type: Article

Abstract

Paper-based microfluidics is a rapidly progressing inter-disciplinary technology driven by the need for low-cost alternatives to conventional point-of-care diagnostic tools. For transport of reagents/analytes, such devices often consist of interconnected hydrophilic fluid-flow channels that are demarcated by hydrophobic barrier walls that extend through the thickness of the paper. Here, we present a laser-based fabrication procedure that uses polymerisation of a photopolymer to produce the required fluidic channels in paper. Experimental results showed that the structures successfully guide the flow of fluids and allow containment of fluids in wells, and hence the technique is suitable for fabrication of paper-based microfluidic devices. The minimum width for the hydrophobic barriers that successfully prevented fluid leakage was ~120 µm and the minimum width for the fluidic channels that can be formed was ~80 µm, the smallest reported so far for paper-based fluidic patterns.

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More information

Accepted/In Press date: 29 September 2014
e-pub ahead of print date: 29 September 2014
Published date: 7 December 2014
Organisations: Optoelectronics Research Centre

Identifiers

Local EPrints ID: 384363
URI: https://eprints.soton.ac.uk/id/eprint/384363
ISSN: 1473-0197
PURE UUID: 7f5548b7-360e-4219-b41b-4701c6e0ecf2
ORCID for I.N. Katis: ORCID iD orcid.org/0000-0002-2016-557X
ORCID for B. Mills: ORCID iD orcid.org/0000-0002-1784-1012
ORCID for P. Shardlow: ORCID iD orcid.org/0000-0003-0459-0581
ORCID for R.W. Eason: ORCID iD orcid.org/0000-0001-9704-2204

Catalogue record

Date deposited: 02 Dec 2015 14:51
Last modified: 03 Dec 2019 02:06

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Contributors

Author: C.L. Sones
Author: I.N. Katis ORCID iD
Author: P.J.W. He
Author: B. Mills ORCID iD
Author: M.F. Namiq
Author: P. Shardlow ORCID iD
Author: M. Ibsen
Author: R.W. Eason ORCID iD

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