Identification of genes regulated by Wnt/beta-catenin pathway and involved in apoptosis via microarray analysis.
Identification of genes regulated by Wnt/beta-catenin pathway and involved in apoptosis via microarray analysis.
Coupling RNAi knockdown with microarray and RT-PCR analyses proves to be a versatile strategy for identifying genes regulated by Wnt/beta-catenin pathway and for a better understanding the role of this pathway in apoptosis. Some of the identified beta-catenin/TCF directed or indirected target genes may represent excellent targets to limit tumor growth.
1-11
Huang, Moli
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Wang, Yihua
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Sun, Daochun
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Zhu, Hongxia
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Yin, Yanbing
a31eff3c-d0f6-42af-b917-2aa2deb83c2d
Zhang, Wei
fa6d7061-bfce-48c0-879c-925302213c1a
Yang, Shangbin
eb128acb-bc5c-4c4b-a96a-ae9f3b082b7e
Quan, Lanping
75ae7877-e353-41d9-ba4b-c3ad47e5a69c
Bai, Jinfeng
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Wang, Shengqi
3e324a48-28ea-4fbc-abb2-715d790bf1a8
Chen, Quan
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Li, Songgang
c6ea731d-8a3e-44e1-bde7-9ee761afe360
Xu, Ningzhi
7e2ddae3-ef56-4e9e-9ccb-4fddbcdf045f
7 September 2006
Huang, Moli
e4e2a533-4802-44c0-b103-5473e293b5ff
Wang, Yihua
f5044a95-60a7-42d2-87d6-5f1f789e3a7e
Sun, Daochun
d9816aa4-dbc4-43ab-9db8-b55785f72e7a
Zhu, Hongxia
34c74461-aab8-4886-8ed4-f80438fa2083
Yin, Yanbing
a31eff3c-d0f6-42af-b917-2aa2deb83c2d
Zhang, Wei
fa6d7061-bfce-48c0-879c-925302213c1a
Yang, Shangbin
eb128acb-bc5c-4c4b-a96a-ae9f3b082b7e
Quan, Lanping
75ae7877-e353-41d9-ba4b-c3ad47e5a69c
Bai, Jinfeng
66033867-936e-4551-96db-61c624e804f1
Wang, Shengqi
3e324a48-28ea-4fbc-abb2-715d790bf1a8
Chen, Quan
d1a4aa2c-74db-406a-a073-1ea02d3560c6
Li, Songgang
c6ea731d-8a3e-44e1-bde7-9ee761afe360
Xu, Ningzhi
7e2ddae3-ef56-4e9e-9ccb-4fddbcdf045f
Huang, Moli, Wang, Yihua, Sun, Daochun, Zhu, Hongxia, Yin, Yanbing, Zhang, Wei, Yang, Shangbin, Quan, Lanping, Bai, Jinfeng, Wang, Shengqi, Chen, Quan, Li, Songgang and Xu, Ningzhi
(2006)
Identification of genes regulated by Wnt/beta-catenin pathway and involved in apoptosis via microarray analysis.
BMC cancer, 6 (221), .
(doi:10.1186/1471-2407-6-221).
(PMID:16959035)
Abstract
Coupling RNAi knockdown with microarray and RT-PCR analyses proves to be a versatile strategy for identifying genes regulated by Wnt/beta-catenin pathway and for a better understanding the role of this pathway in apoptosis. Some of the identified beta-catenin/TCF directed or indirected target genes may represent excellent targets to limit tumor growth.
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art%3A10.1186%2F1471-2407-6-221.pdf
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Accepted/In Press date: 7 September 2006
Published date: 7 September 2006
Organisations:
Centre for Biological Sciences
Identifiers
Local EPrints ID: 385922
URI: http://eprints.soton.ac.uk/id/eprint/385922
ISSN: 1471-2407
PURE UUID: 465c2223-bcd9-41cf-9cd6-87108a6c94b1
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Date deposited: 26 Jan 2016 11:41
Last modified: 15 Mar 2024 03:52
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Contributors
Author:
Moli Huang
Author:
Daochun Sun
Author:
Hongxia Zhu
Author:
Yanbing Yin
Author:
Wei Zhang
Author:
Shangbin Yang
Author:
Lanping Quan
Author:
Jinfeng Bai
Author:
Shengqi Wang
Author:
Quan Chen
Author:
Songgang Li
Author:
Ningzhi Xu
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