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Organophotocatalytic synthesis of phosphoramidates

Organophotocatalytic synthesis of phosphoramidates
Organophotocatalytic synthesis of phosphoramidates
We describe the use of visible light in conjunction with an organic dye for the synthesis of phosphoramidates. Cross dehydrogenative coupling reactions between phosphites and amines are reported using organic dyes and light as catalysts for the first time. It is not only a novel application of organic dyes but also fulfils the requirement of sustainability and green chemistry avoiding the use of chromatographic purification techniques. The product was simply isolated from the reaction mixture via an acid-base work-up procedure, rendering the pure product in good yields.
cross dehydrogenative coupling (CDC) reactions, dyes, green chemistry, phosphoramidates, photocatalysis
1615-4150
719-723
Meazza, Marta
c4665645-8c77-4cfd-aa02-6bcc3341c1aa
Kowalczuk, Agnieszka
5acf6d9e-655e-4cd8-897f-f5e20f75a1d1
Shirley, Luke
18fb5c30-94b6-40f7-8db4-1db1ea1b0126
Yang, Jung Woon
70327194-b21c-402c-83c0-4474fb47db63
Hao, Guo
6b2feec3-288a-40dd-bed4-44ba1e885f79
Rios, Ramon
609bedf2-e886-4d62-a676-a32b6f8c1441
Meazza, Marta
c4665645-8c77-4cfd-aa02-6bcc3341c1aa
Kowalczuk, Agnieszka
5acf6d9e-655e-4cd8-897f-f5e20f75a1d1
Shirley, Luke
18fb5c30-94b6-40f7-8db4-1db1ea1b0126
Yang, Jung Woon
70327194-b21c-402c-83c0-4474fb47db63
Hao, Guo
6b2feec3-288a-40dd-bed4-44ba1e885f79
Rios, Ramon
609bedf2-e886-4d62-a676-a32b6f8c1441

Meazza, Marta, Kowalczuk, Agnieszka and Shirley, Luke et al. (2016) Organophotocatalytic synthesis of phosphoramidates. Advanced Synthesis & Catalysis, 358 (5), 719-723. (doi:10.1002/adsc.201501068).

Record type: Article

Abstract

We describe the use of visible light in conjunction with an organic dye for the synthesis of phosphoramidates. Cross dehydrogenative coupling reactions between phosphites and amines are reported using organic dyes and light as catalysts for the first time. It is not only a novel application of organic dyes but also fulfils the requirement of sustainability and green chemistry avoiding the use of chromatographic purification techniques. The product was simply isolated from the reaction mixture via an acid-base work-up procedure, rendering the pure product in good yields.

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Manuscript (Adv. Synth. Catal.).pdf - Accepted Manuscript
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More information

Accepted/In Press date: 10 December 2015
Published date: 11 February 2016
Keywords: cross dehydrogenative coupling (CDC) reactions, dyes, green chemistry, phosphoramidates, photocatalysis
Organisations: Organic Chemistry: Synthesis, Catalysis and Flow

Identifiers

Local EPrints ID: 388512
URI: http://eprints.soton.ac.uk/id/eprint/388512
ISSN: 1615-4150
PURE UUID: e3037847-db1c-447d-86c0-0e58a4985d79
ORCID for Marta Meazza: ORCID iD orcid.org/0000-0003-4382-0626
ORCID for Ramon Rios: ORCID iD orcid.org/0000-0002-3843-8521

Catalogue record

Date deposited: 29 Feb 2016 09:49
Last modified: 14 Mar 2024 22:58

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Contributors

Author: Marta Meazza ORCID iD
Author: Agnieszka Kowalczuk
Author: Luke Shirley
Author: Jung Woon Yang
Author: Guo Hao
Author: Ramon Rios ORCID iD

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