Allergy to furry animals: new insights, diagnostic approaches, and challenges
Allergy to furry animals: new insights, diagnostic approaches, and challenges
The prevalence of allergy to furry animals has been increasing, and allergy to cats, dogs, or both is considered a major risk factor for the development of asthma and rhinitis. An important step forward in the diagnosis of allergy to furry animals has been made with the introduction of molecular-based allergy diagnostics. A workshop on furry animals was convened to provide an up-to-date assessment of our understanding of (1) the exposure and immune response to the major mammalian allergens, (2) the relationship of these responses (particularly those to specific proteins or components) to symptoms, and (3) the relevance of these specific antibody responses to current or future investigation of patients presenting with allergic diseases. In this review research results discussed at the workshop are presented, including the effect of concomitant exposures from other allergens or microorganisms, the significance of the community prevalence of furry animals, molecular-based allergy diagnostics, and a detailed discussion of cat and dog components.
molecular-based allergy diagnostics, allergy, allergens, furry animals, cats, dogs, allergic asthma, allergic rhinitis, pork-cat syndrome
616-625
Konradsen, Jon R.
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Fujisawa, Takao
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van Hage, Marianne
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Hedlin, Gunilla
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Hilger, Christiane
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Kleine-Tebbe, Jörg
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Matsui, Elizabeth C.
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Roberts, Graham
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Rönmark, Eva
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Platts-Mills, Thomas A.E.
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March 2015
Konradsen, Jon R.
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Fujisawa, Takao
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van Hage, Marianne
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Hedlin, Gunilla
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Hilger, Christiane
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Kleine-Tebbe, Jörg
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Matsui, Elizabeth C.
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Roberts, Graham
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Rönmark, Eva
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Platts-Mills, Thomas A.E.
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Konradsen, Jon R., Fujisawa, Takao, van Hage, Marianne, Hedlin, Gunilla, Hilger, Christiane, Kleine-Tebbe, Jörg, Matsui, Elizabeth C., Roberts, Graham, Rönmark, Eva and Platts-Mills, Thomas A.E.
(2015)
Allergy to furry animals: new insights, diagnostic approaches, and challenges.
Journal of Allergy and Clinical Immunology, 135 (3), .
(doi:10.1016/j.jaci.2014.08.026).
(PMID:26051956)
Abstract
The prevalence of allergy to furry animals has been increasing, and allergy to cats, dogs, or both is considered a major risk factor for the development of asthma and rhinitis. An important step forward in the diagnosis of allergy to furry animals has been made with the introduction of molecular-based allergy diagnostics. A workshop on furry animals was convened to provide an up-to-date assessment of our understanding of (1) the exposure and immune response to the major mammalian allergens, (2) the relationship of these responses (particularly those to specific proteins or components) to symptoms, and (3) the relevance of these specific antibody responses to current or future investigation of patients presenting with allergic diseases. In this review research results discussed at the workshop are presented, including the effect of concomitant exposures from other allergens or microorganisms, the significance of the community prevalence of furry animals, molecular-based allergy diagnostics, and a detailed discussion of cat and dog components.
Text
KONRADSEN Allergy to furry animals J Allergy Clin Immunol 2015.pdf
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Accepted/In Press date: 5 August 2014
e-pub ahead of print date: 3 October 2014
Published date: March 2015
Keywords:
molecular-based allergy diagnostics, allergy, allergens, furry animals, cats, dogs, allergic asthma, allergic rhinitis, pork-cat syndrome
Organisations:
Human Development & Health
Identifiers
Local EPrints ID: 388688
URI: http://eprints.soton.ac.uk/id/eprint/388688
ISSN: 0091-6749
PURE UUID: 908128bf-bdda-4628-9d8c-024377132768
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Date deposited: 02 Mar 2016 09:47
Last modified: 15 Mar 2024 03:22
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Contributors
Author:
Jon R. Konradsen
Author:
Takao Fujisawa
Author:
Marianne van Hage
Author:
Gunilla Hedlin
Author:
Christiane Hilger
Author:
Jörg Kleine-Tebbe
Author:
Elizabeth C. Matsui
Author:
Eva Rönmark
Author:
Thomas A.E. Platts-Mills
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