Association between micronutrient levels and chronic spontaneous urticaria
Association between micronutrient levels and chronic spontaneous urticaria
Previous reports have suggested a possible role for vitamin D in the etiology of chronic spontaneous urticaria (CSU); however, little information is available regarding the role of other micronutrients. We, therefore, analyzed vitamin D, vitamin B12, and ferritin levels in CSU patients (n = 282) from a preexisting database at Southampton General Hospital. Data were compared against mean micronutrient levels of the general population of the UK, obtained from the National Diet and Nutrition Survey. Vitamin D levels of CSU patients were found to be higher than those of the general UK population (P = 0.001). B12 levels were lower in patients with CSU (P < 0.001) than in the general population. Ferritin levels were found to be lower in male CSU patients than in the general male population (P = 0.009). This association between low B12 and iron levels and CSU might indicate a causal link, with micronutrient replacement as a potential therapeutic option.
1-3
Wu, Cheng-Han
aabdce6f-6ecd-4d59-b9ff-4b018f0bd4d7
Eren, Efrem
ac449fc8-4ae2-4efd-ad91-9dcea3f355e2
Ardern-Jones, Michael Roger
7ac43c24-94ab-4d19-ba69-afaa546bec90
Venter, Carina
a9b7dd5e-b0cb-4068-be82-e15b587cc20b
2015
Wu, Cheng-Han
aabdce6f-6ecd-4d59-b9ff-4b018f0bd4d7
Eren, Efrem
ac449fc8-4ae2-4efd-ad91-9dcea3f355e2
Ardern-Jones, Michael Roger
7ac43c24-94ab-4d19-ba69-afaa546bec90
Venter, Carina
a9b7dd5e-b0cb-4068-be82-e15b587cc20b
Wu, Cheng-Han, Eren, Efrem, Ardern-Jones, Michael Roger and Venter, Carina
(2015)
Association between micronutrient levels and chronic spontaneous urticaria.
BioMed Research International, 2015 (926167), .
(doi:10.1155/2015/926167).
(PMID:12037402)
Abstract
Previous reports have suggested a possible role for vitamin D in the etiology of chronic spontaneous urticaria (CSU); however, little information is available regarding the role of other micronutrients. We, therefore, analyzed vitamin D, vitamin B12, and ferritin levels in CSU patients (n = 282) from a preexisting database at Southampton General Hospital. Data were compared against mean micronutrient levels of the general population of the UK, obtained from the National Diet and Nutrition Survey. Vitamin D levels of CSU patients were found to be higher than those of the general UK population (P = 0.001). B12 levels were lower in patients with CSU (P < 0.001) than in the general population. Ferritin levels were found to be lower in male CSU patients than in the general male population (P = 0.009). This association between low B12 and iron levels and CSU might indicate a causal link, with micronutrient replacement as a potential therapeutic option.
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Accepted/In Press date: 13 October 2015
Published date: 2015
Organisations:
Clinical & Experimental Sciences
Identifiers
Local EPrints ID: 390060
URI: http://eprints.soton.ac.uk/id/eprint/390060
ISSN: 2314-6133
PURE UUID: a9a39d51-2fb6-413e-991c-d516208b07c6
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Date deposited: 17 Mar 2016 15:29
Last modified: 15 Mar 2024 03:28
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Author:
Cheng-Han Wu
Author:
Efrem Eren
Author:
Carina Venter
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