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Hand pains in women and men in early rheumatoid arthritis, a one year follow-up after diagnosis. The Swedish TIRA project

Hand pains in women and men in early rheumatoid arthritis, a one year follow-up after diagnosis. The Swedish TIRA project
Hand pains in women and men in early rheumatoid arthritis, a one year follow-up after diagnosis. The Swedish TIRA project
Purpose: This research analysed general pain intensity, hand pain at rest and hand pain during activity in women and men in early rheumatoid arhtritis (RA).

Method: Out of the 454 patients that were recruited into the Swedish early RA project "TIRA" the 373 patients (67% women) that remained at 12 months follow-up are reported here. Disease activity 28 joint score (DAS-28), disability (Health Assessment Questionnaire?=?HAQ) and pain (VAS) were recorded at inclusion and after 3 (M3), 6 (M6) and 12 (M12) months. General pain, hand pain during rest, hand pain during test of grip force as assessed by Grippit™, prescribed disease-modifying anti-inflammatory drugs (DMARDs) and hand dominance were recorded.

Results: DAS-28 and HAQ scores were high at inclusion and improved thereafter in both women and men. There were no significant differences between sexes at inclusion but women had higher DAS-28 and HAQ at all follow-ups. Women were more often prescribed DMARDs than were men. In both women and men all pain types were significantly lower at follow-up compared to at inclusion and women reported higher pain than men at follow-ups. The pain types differed significantly from each other at inclusion into TIRA, general pain was highest and hand pain during rest was lowest. There were no significant differences in hand pain related to hand dominance or between right and left hands.

Conclusions: Disease activity, disability and pain were high at inclusion and reduced over the first year. Despite more DMARDs prescribed in women than in men, women were more affected than were men. General pain was highest and not surprisingly hand pain during active grip testing was higher than hand pain during rest that was lowest in both sexes. Although our cohort was well controlled, it was evident that hand pain remains a problem. This has implications for rehabilitation and suggests potential ongoing activity limitations that should continue to receive attention from a multi-professional team.

Implications for Rehabilitation:
- General pain and hand pain remain a problem in RA despite today's early intervention and effective disease control with new era biologics.
- The extent of hand pain evidenced in our work gives a more detailed and comprehensive account of pain status.
- Higher hand pain during active grip testing than that during rest indicates a potential relationship to ongoing activity limitation.
- Hand pain assessment can help guiding multi-professional interventions directed to reduce hand pain and thereby probably reduce activity limitations.
disability, grip force, hand function, pain, rehabilitation, sex
0963-8288
1-10
Thyberg, Ingrid
3b579446-b29b-4935-a259-4d7d34bf5363
Dahlström, Örjan
ab061da6-4b2a-4336-915b-cc8873a10ec5
Björk, Mathilda
e71f0d9f-fd14-4b3c-b99c-e17a26c16c62
Stenström, Birgitta
4b1a0ec2-2e71-4e04-b30c-2dd5c624a2b0
Adams, Jo
6e38b8bb-9467-4585-86e4-14062b02bcba
Thyberg, Ingrid
3b579446-b29b-4935-a259-4d7d34bf5363
Dahlström, Örjan
ab061da6-4b2a-4336-915b-cc8873a10ec5
Björk, Mathilda
e71f0d9f-fd14-4b3c-b99c-e17a26c16c62
Stenström, Birgitta
4b1a0ec2-2e71-4e04-b30c-2dd5c624a2b0
Adams, Jo
6e38b8bb-9467-4585-86e4-14062b02bcba

Thyberg, Ingrid, Dahlström, Örjan, Björk, Mathilda, Stenström, Birgitta and Adams, Jo (2016) Hand pains in women and men in early rheumatoid arthritis, a one year follow-up after diagnosis. The Swedish TIRA project. Disability and Rehabilitation, 1-10. (doi:10.3109/09638288.2016.1140835). (PMID:26965161)

Record type: Article

Abstract

Purpose: This research analysed general pain intensity, hand pain at rest and hand pain during activity in women and men in early rheumatoid arhtritis (RA).

Method: Out of the 454 patients that were recruited into the Swedish early RA project "TIRA" the 373 patients (67% women) that remained at 12 months follow-up are reported here. Disease activity 28 joint score (DAS-28), disability (Health Assessment Questionnaire?=?HAQ) and pain (VAS) were recorded at inclusion and after 3 (M3), 6 (M6) and 12 (M12) months. General pain, hand pain during rest, hand pain during test of grip force as assessed by Grippit™, prescribed disease-modifying anti-inflammatory drugs (DMARDs) and hand dominance were recorded.

Results: DAS-28 and HAQ scores were high at inclusion and improved thereafter in both women and men. There were no significant differences between sexes at inclusion but women had higher DAS-28 and HAQ at all follow-ups. Women were more often prescribed DMARDs than were men. In both women and men all pain types were significantly lower at follow-up compared to at inclusion and women reported higher pain than men at follow-ups. The pain types differed significantly from each other at inclusion into TIRA, general pain was highest and hand pain during rest was lowest. There were no significant differences in hand pain related to hand dominance or between right and left hands.

Conclusions: Disease activity, disability and pain were high at inclusion and reduced over the first year. Despite more DMARDs prescribed in women than in men, women were more affected than were men. General pain was highest and not surprisingly hand pain during active grip testing was higher than hand pain during rest that was lowest in both sexes. Although our cohort was well controlled, it was evident that hand pain remains a problem. This has implications for rehabilitation and suggests potential ongoing activity limitations that should continue to receive attention from a multi-professional team.

Implications for Rehabilitation:
- General pain and hand pain remain a problem in RA despite today's early intervention and effective disease control with new era biologics.
- The extent of hand pain evidenced in our work gives a more detailed and comprehensive account of pain status.
- Higher hand pain during active grip testing than that during rest indicates a potential relationship to ongoing activity limitation.
- Hand pain assessment can help guiding multi-professional interventions directed to reduce hand pain and thereby probably reduce activity limitations.

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Accepted/In Press date: 7 January 2016
Published date: 11 March 2016
Keywords: disability, grip force, hand function, pain, rehabilitation, sex
Organisations: Faculty of Health Sciences

Identifiers

Local EPrints ID: 390202
URI: http://eprints.soton.ac.uk/id/eprint/390202
ISSN: 0963-8288
PURE UUID: 26d7d337-4c57-4cc3-b881-fcfabad5e34c
ORCID for Jo Adams: ORCID iD orcid.org/0000-0003-1765-7060

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Date deposited: 22 Mar 2016 10:01
Last modified: 15 Mar 2024 02:49

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Contributors

Author: Ingrid Thyberg
Author: Örjan Dahlström
Author: Mathilda Björk
Author: Birgitta Stenström
Author: Jo Adams ORCID iD

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