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Regional assessment of lung function using thin-plate splines to align structural and functional imaging

Regional assessment of lung function using thin-plate splines to align structural and functional imaging
Regional assessment of lung function using thin-plate splines to align structural and functional imaging
Ventilation / perfusion (VQ) Single Photon Emission Computed Tomography (SPECT) imaging provides 3D data of the regional distribution of ventilation and perfusion throughout the lung, but interpretation of the results is difficult without reference to the underlying lung anatomy. Multi-Slice Computed Tomography (MSCT) imaging is able to provide significant anatomical detail in the lung, allowing delineation of regional features such as the lobes. The purpose of this work was to develop software tools to allow the alignment of regions delineated from the MSCT scans, with the corresponding SPECT data, to allow measurements of VQ to be made for anatomically meaningful regions. The technique developed was based on the use of thin-plate splines and the results showed that it was able to provide good alignment between the MSCT and SPECT data.
978-1-4244-9270-1
2928-2931
Bennett, M.J.
6df5585a-3d93-4870-8797-389759fc82c7
Havelock, T.
8f9aa3be-a768-4a7b-bcd4-79656e2b188c
Bennett, S.
2fd58f36-ee42-44d2-b27b-f0fe7c6c5c2c
Conway, J.
bbe9a2e4-fb85-4d4a-a38c-0c1832c32d06
Fleming, J.
6876b2b5-6252-465d-8853-216583e4c8a4
Howarth, P.H.
ff19c8c4-86b0-4a88-8f76-b3d87f142a21
Bennett, M.J.
6df5585a-3d93-4870-8797-389759fc82c7
Havelock, T.
8f9aa3be-a768-4a7b-bcd4-79656e2b188c
Bennett, S.
2fd58f36-ee42-44d2-b27b-f0fe7c6c5c2c
Conway, J.
bbe9a2e4-fb85-4d4a-a38c-0c1832c32d06
Fleming, J.
6876b2b5-6252-465d-8853-216583e4c8a4
Howarth, P.H.
ff19c8c4-86b0-4a88-8f76-b3d87f142a21

Bennett, M.J., Havelock, T., Bennett, S., Conway, J., Fleming, J. and Howarth, P.H. (2015) Regional assessment of lung function using thin-plate splines to align structural and functional imaging. 37th Annual International Conference of the IEEE, Milano, Italy. 25 - 29 Aug 2015. pp. 2928-2931 . (doi:10.1109/EMBC.2015.7319005).

Record type: Conference or Workshop Item (Paper)

Abstract

Ventilation / perfusion (VQ) Single Photon Emission Computed Tomography (SPECT) imaging provides 3D data of the regional distribution of ventilation and perfusion throughout the lung, but interpretation of the results is difficult without reference to the underlying lung anatomy. Multi-Slice Computed Tomography (MSCT) imaging is able to provide significant anatomical detail in the lung, allowing delineation of regional features such as the lobes. The purpose of this work was to develop software tools to allow the alignment of regions delineated from the MSCT scans, with the corresponding SPECT data, to allow measurements of VQ to be made for anatomically meaningful regions. The technique developed was based on the use of thin-plate splines and the results showed that it was able to provide good alignment between the MSCT and SPECT data.

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More information

Published date: August 2015
Venue - Dates: 37th Annual International Conference of the IEEE, Milano, Italy, 2015-08-25 - 2015-08-29
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 390334
URI: http://eprints.soton.ac.uk/id/eprint/390334
ISBN: 978-1-4244-9270-1
PURE UUID: 34aa4560-a71f-4305-a98b-2f07f8d7713e
ORCID for J. Conway: ORCID iD orcid.org/0000-0001-6464-1526

Catalogue record

Date deposited: 24 Mar 2016 11:22
Last modified: 14 Mar 2024 23:16

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Contributors

Author: M.J. Bennett
Author: T. Havelock
Author: S. Bennett
Author: J. Conway ORCID iD
Author: J. Fleming
Author: P.H. Howarth

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