Unexpected formation of ?-lactams and penem isosteres from mesoionics: sequential ring-opening-rearrangement of [3+2] cycloadducts
Unexpected formation of ?-lactams and penem isosteres from mesoionics: sequential ring-opening-rearrangement of [3+2] cycloadducts
A novel and simple method has been developed to obtain penem analogs with biologically interesting functionalities, which combines aromatic aldehydes with thioisomunchnones, a readily available class of mesoionic heterocycles.
diastereoselective synthesis, cycloaddition chemistry, systems
1589-1590
Avalos, Martin
75b746b8-64d3-4451-be7a-c7c536ed6602
Babiano, Reyes
b7ffd91c-bacd-4372-ab99-fc30ac2450ae
Cintas, Pedro
29979233-8382-47a8-bde7-1faf4869308c
Jiménez, José L.
074cc8fd-9ea1-41fc-b8b6-551d26e5fcd3
López, Ignacio
215a6254-7805-40e9-a90d-878a966e6dbb
Palacios, Juan C.
2c06e379-89b3-46b1-95c8-7f5057732f9f
Hursthouse, Michael B.
57a2ddf9-b1b3-4f38-bfe9-ef2f526388da
Light, Mark E.
13b5eb33-3114-4fb7-8500-90ce69e9933c
1999
Avalos, Martin
75b746b8-64d3-4451-be7a-c7c536ed6602
Babiano, Reyes
b7ffd91c-bacd-4372-ab99-fc30ac2450ae
Cintas, Pedro
29979233-8382-47a8-bde7-1faf4869308c
Jiménez, José L.
074cc8fd-9ea1-41fc-b8b6-551d26e5fcd3
López, Ignacio
215a6254-7805-40e9-a90d-878a966e6dbb
Palacios, Juan C.
2c06e379-89b3-46b1-95c8-7f5057732f9f
Hursthouse, Michael B.
57a2ddf9-b1b3-4f38-bfe9-ef2f526388da
Light, Mark E.
13b5eb33-3114-4fb7-8500-90ce69e9933c
Avalos, Martin, Babiano, Reyes, Cintas, Pedro, Jiménez, José L., López, Ignacio, Palacios, Juan C., Hursthouse, Michael B. and Light, Mark E.
(1999)
Unexpected formation of ?-lactams and penem isosteres from mesoionics: sequential ring-opening-rearrangement of [3+2] cycloadducts.
Chemical Communications, (16), .
(doi:10.1039/a904333k).
Abstract
A novel and simple method has been developed to obtain penem analogs with biologically interesting functionalities, which combines aromatic aldehydes with thioisomunchnones, a readily available class of mesoionic heterocycles.
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Published date: 1999
Keywords:
diastereoselective synthesis, cycloaddition chemistry, systems
Identifiers
Local EPrints ID: 39135
URI: http://eprints.soton.ac.uk/id/eprint/39135
ISSN: 1359-7345
PURE UUID: 4809896c-d454-48b0-9260-a38c90cafcc1
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Date deposited: 18 Jul 2006
Last modified: 15 Mar 2024 08:11
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Contributors
Author:
Martin Avalos
Author:
Reyes Babiano
Author:
Pedro Cintas
Author:
José L. Jiménez
Author:
Ignacio López
Author:
Juan C. Palacios
Author:
Mark E. Light
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