Depth-resolved full-field measurement of corneal deformation by optical coherence tomography and digital volume correlation
Depth-resolved full-field measurement of corneal deformation by optical coherence tomography and digital volume correlation
The study of vertebrate eye cornea is an interdisciplinary subject and the research on its mechanical properties has significant importance in ophthalmology. The measurement of depth-resolved 3D full-field deformation behaviour of cornea under changing intraocular pressure is a useful method to study the local corneal mechanical properties. In this work, optical coherence tomography was adopted to reconstruct the internal structure of a porcine cornea inflated from 15 to 18.75 mmHg (close to the physical porcine intraocular pressure) in the form of 3D image sequences. An effective method has been developed to correct the commonly seen refraction induced distortions in the optical coherence tomography reconstructions, based on Fermat’s principle. The 3D deformation field was then determined by performing digital volume correlation on these corrected 3D reconstructions. A simple finite element model of the inflation test was developed and the predicted values were compared against digital volume correlation results, showing good overall agreement.
1203-1217
Fu, J.
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Haghighi-Abayneh, M.
04413210-bc55-429f-9578-dbb32af18545
Pierron, F.
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Ruiz, P.D.
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2016
Fu, J.
76cdabe5-fdd1-49e0-ba72-1524bca50df9
Haghighi-Abayneh, M.
04413210-bc55-429f-9578-dbb32af18545
Pierron, F.
a1fb4a70-6f34-4625-bc23-fcb6996b79b4
Ruiz, P.D.
ea552047-ae33-4b78-89d2-6260a5bde2d3
Fu, J., Haghighi-Abayneh, M., Pierron, F. and Ruiz, P.D.
(2016)
Depth-resolved full-field measurement of corneal deformation by optical coherence tomography and digital volume correlation.
Experimental Mechanics, 56 (7), .
(doi:10.1007/s11340-016-0165-y).
Abstract
The study of vertebrate eye cornea is an interdisciplinary subject and the research on its mechanical properties has significant importance in ophthalmology. The measurement of depth-resolved 3D full-field deformation behaviour of cornea under changing intraocular pressure is a useful method to study the local corneal mechanical properties. In this work, optical coherence tomography was adopted to reconstruct the internal structure of a porcine cornea inflated from 15 to 18.75 mmHg (close to the physical porcine intraocular pressure) in the form of 3D image sequences. An effective method has been developed to correct the commonly seen refraction induced distortions in the optical coherence tomography reconstructions, based on Fermat’s principle. The 3D deformation field was then determined by performing digital volume correlation on these corrected 3D reconstructions. A simple finite element model of the inflation test was developed and the predicted values were compared against digital volume correlation results, showing good overall agreement.
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Accepted/In Press date: 11 April 2016
e-pub ahead of print date: 15 April 2016
Published date: 2016
Organisations:
Mechatronics
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Local EPrints ID: 392842
URI: http://eprints.soton.ac.uk/id/eprint/392842
ISSN: 1741-2765
PURE UUID: 691260c7-3a9a-4fa7-a969-82978c62be60
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Date deposited: 18 Apr 2016 11:04
Last modified: 15 Mar 2024 05:30
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Contributors
Author:
J. Fu
Author:
M. Haghighi-Abayneh
Author:
P.D. Ruiz
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