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Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster

Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster
Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster
The Drosophila MIND/MIS12 and NDC80 complexes and the Spc105 protein, like their counterparts from other eukaryotic species, are essential for chromosome congression and segregation, but are highly diverged in sequence. Hierarchical dependence relationships of individual proteins regulate the assembly of Drosophila kinetochore complexes in a manner similar, but not identical, to other organisms.
1932-6203
1-13
Przewloka, Marcin
9b25e73c-ec15-43df-a5a4-ac9574bb20ab
Zhang, Wei
fa6d7061-bfce-48c0-879c-925302213c1a
Costa, Patricia
ad278e79-7661-4418-93d9-3191f91c2343
Archambault, Vincent
3654cc6d-d3f9-4404-8ae5-9d8af8b008dc
D'Avino, Pier Paolo
0e659e0c-c3a7-4344-8850-3364810b9445
Lilley, Kathryn S.
84ad87ab-f75d-4686-8ab6-90fcfbdf0ec0
Laue, Ernest D.
9bfea318-d6a1-493a-9055-41a9f9e06f17
McAinsh, Andrew D.
c355faa1-9466-4e45-a736-7a6a5aa819c2
Glover, David M.
cca9cd19-3e1e-4906-b418-41876c1f9c61
Przewloka, Marcin
9b25e73c-ec15-43df-a5a4-ac9574bb20ab
Zhang, Wei
fa6d7061-bfce-48c0-879c-925302213c1a
Costa, Patricia
ad278e79-7661-4418-93d9-3191f91c2343
Archambault, Vincent
3654cc6d-d3f9-4404-8ae5-9d8af8b008dc
D'Avino, Pier Paolo
0e659e0c-c3a7-4344-8850-3364810b9445
Lilley, Kathryn S.
84ad87ab-f75d-4686-8ab6-90fcfbdf0ec0
Laue, Ernest D.
9bfea318-d6a1-493a-9055-41a9f9e06f17
McAinsh, Andrew D.
c355faa1-9466-4e45-a736-7a6a5aa819c2
Glover, David M.
cca9cd19-3e1e-4906-b418-41876c1f9c61

Przewloka, Marcin, Zhang, Wei, Costa, Patricia, Archambault, Vincent, D'Avino, Pier Paolo, Lilley, Kathryn S., Laue, Ernest D., McAinsh, Andrew D. and Glover, David M. (2007) Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster. PLoS ONE, 2 (5), 1-13. (doi:10.1371/journal.pone.0000478). (PMID:17534428)

Record type: Article

Abstract

The Drosophila MIND/MIS12 and NDC80 complexes and the Spc105 protein, like their counterparts from other eukaryotic species, are essential for chromosome congression and segregation, but are highly diverged in sequence. Hierarchical dependence relationships of individual proteins regulate the assembly of Drosophila kinetochore complexes in a manner similar, but not identical, to other organisms.

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More information

Accepted/In Press date: 1 May 2007
Published date: 30 May 2007
Organisations: Molecular and Cellular, Centre for Biological Sciences

Identifiers

Local EPrints ID: 393867
URI: http://eprints.soton.ac.uk/id/eprint/393867
ISSN: 1932-6203
PURE UUID: 6222e593-710c-4428-9fe4-2b54dc8892e7
ORCID for Marcin Przewloka: ORCID iD orcid.org/0000-0002-0329-9162

Catalogue record

Date deposited: 26 May 2016 11:20
Last modified: 26 Nov 2019 01:31

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