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Mechanically coupled bulk-mode dual resonator mass sensor

Mechanically coupled bulk-mode dual resonator mass sensor
Mechanically coupled bulk-mode dual resonator mass sensor
The adaptation of micro- and nanomechanical resonators as mass balances for biochemical sensing has received much attention in recent years due to the potential for very high resolution and electrical readout of target analyte in a label-free format. However, several implementation challenges arise from the necessity of operation in compatible biological buffer solutions. These challenges include minimizing undesired effects of fluid-structure interaction and buffer interference with signal transduction. Electrical readout of the sensor response is complicated by coupling to the electrical properties of the buffer solution and voltage limitations due to the possibility of undesired electrochemical reactions on the sensor surface. To address this problem we propose a novel dual resonator platform, wherein electrical transduction and sensing are spatially separated onto two different mechanically coupled resonators. In this work, we demonstrate the functionality of the dual resonator system as a mass sensing platform, with a mass responsivity of 37 Hz/ng.
1454-1457
Lin, Angel T.-H.
9a64197d-3714-449c-9720-9ef4ea5f2689
Yan, Jize
786dc090-843b-435d-adbe-1d35e8fc5828
Seshia, Ashwin A.
6fe2b5b5-e451-41e2-a23a-601c9faf7d8a
Lin, Angel T.-H.
9a64197d-3714-449c-9720-9ef4ea5f2689
Yan, Jize
786dc090-843b-435d-adbe-1d35e8fc5828
Seshia, Ashwin A.
6fe2b5b5-e451-41e2-a23a-601c9faf7d8a

Lin, Angel T.-H., Yan, Jize and Seshia, Ashwin A. (2010) Mechanically coupled bulk-mode dual resonator mass sensor [in special issue: Eurosensor XXIV Conference] Procedia Engineering, 5, pp. 1454-1457.

Record type: Article

Abstract

The adaptation of micro- and nanomechanical resonators as mass balances for biochemical sensing has received much attention in recent years due to the potential for very high resolution and electrical readout of target analyte in a label-free format. However, several implementation challenges arise from the necessity of operation in compatible biological buffer solutions. These challenges include minimizing undesired effects of fluid-structure interaction and buffer interference with signal transduction. Electrical readout of the sensor response is complicated by coupling to the electrical properties of the buffer solution and voltage limitations due to the possibility of undesired electrochemical reactions on the sensor surface. To address this problem we propose a novel dual resonator platform, wherein electrical transduction and sensing are spatially separated onto two different mechanically coupled resonators. In this work, we demonstrate the functionality of the dual resonator system as a mass sensing platform, with a mass responsivity of 37 Hz/ng.

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e-pub ahead of print date: 23 October 2010
Organisations: Nanoelectronics and Nanotechnology

Identifiers

Local EPrints ID: 394193
URI: http://eprints.soton.ac.uk/id/eprint/394193
PURE UUID: 4fbefd3a-c3b0-4467-b351-7001640abc05
ORCID for Jize Yan: ORCID iD orcid.org/0000-0002-2886-2847

Catalogue record

Date deposited: 01 Jun 2016 15:53
Last modified: 11 Nov 2017 06:35

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Contributors

Author: Angel T.-H. Lin
Author: Jize Yan ORCID iD
Author: Ashwin A. Seshia

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