AC and phase sensing of nanowires for biosensing
AC and phase sensing of nanowires for biosensing
Silicon nanowires are label-free sensors that allow real-time measurements. They are economical and pave the road for point-of-care applications but require complex readout and skilled personnel. We propose a new model and technique for sensing nanowire sensors using alternating currents (AC) to capture both magnitude and phase information from the sensor. This approach combines the advantages of complex impedance spectroscopy with the noise reduction performances of lock-in techniques. Experimental results show how modifications of the sensors with different surface chemistries lead to the same direct-current (DC) response but can be discerned using the AC approach.
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Crescentini, Marco
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Rossi, Michele
e09fb28f-913c-4204-b350-e462d2f6440f
Ashburn, Peter
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Lombardini, Marta
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Sangiorgi, Enrico
0c75660c-f20c-42ae-bacc-5cae33fd00cf
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Tartagni, Marco
665c139f-e76b-49e2-8cf7-199478891464
19 April 2016
Crescentini, Marco
568e8046-74bd-449f-8794-889643147059
Rossi, Michele
e09fb28f-913c-4204-b350-e462d2f6440f
Ashburn, Peter
68cef6b7-205b-47aa-9efb-f1f09f5c1038
Lombardini, Marta
c8653079-b66c-49ca-ac59-93c3d17b26a4
Sangiorgi, Enrico
0c75660c-f20c-42ae-bacc-5cae33fd00cf
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Tartagni, Marco
665c139f-e76b-49e2-8cf7-199478891464
Crescentini, Marco, Rossi, Michele, Ashburn, Peter, Lombardini, Marta, Sangiorgi, Enrico, Morgan, Hywel and Tartagni, Marco
(2016)
AC and phase sensing of nanowires for biosensing.
Biosensors, 6 (2), .
(doi:10.3390/bios6020015).
Abstract
Silicon nanowires are label-free sensors that allow real-time measurements. They are economical and pave the road for point-of-care applications but require complex readout and skilled personnel. We propose a new model and technique for sensing nanowire sensors using alternating currents (AC) to capture both magnitude and phase information from the sensor. This approach combines the advantages of complex impedance spectroscopy with the noise reduction performances of lock-in techniques. Experimental results show how modifications of the sensors with different surface chemistries lead to the same direct-current (DC) response but can be discerned using the AC approach.
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Accepted/In Press date: 9 April 2016
e-pub ahead of print date: 19 April 2016
Published date: 19 April 2016
Organisations:
Nanoelectronics and Nanotechnology
Identifiers
Local EPrints ID: 394524
URI: http://eprints.soton.ac.uk/id/eprint/394524
ISSN: 0265-928X
PURE UUID: 32dda2fb-76b0-45ca-80ae-5784ecb57c9b
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Date deposited: 19 May 2016 15:52
Last modified: 15 Mar 2024 03:18
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Contributors
Author:
Marco Crescentini
Author:
Michele Rossi
Author:
Marta Lombardini
Author:
Enrico Sangiorgi
Author:
Hywel Morgan
Author:
Marco Tartagni
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