Guidance on conducting systematic reviews/meta-analyses of pharmacoepidemiological studies of safety outcomes: the gap is now filled
Guidance on conducting systematic reviews/meta-analyses of pharmacoepidemiological studies of safety outcomes: the gap is now filled
Until recently, no comprehensive guidance specifically on the conduction of systematic reviews and meta-analyses of pharmacoepidemiological studies of safety outcomes was available. In December 2015, the European Network of Centres for Pharmacoepidemiology and Pharamacovigilance (ENCePP), a network coordinated by the European Medicines Agency, published their ‘Guidance on conducting systematic reviews and meta-analyses of completed comparative pharmacoepidemiological studies of safety outcomes’, filling an important gap in the field. This paper highlights the ENCePP recommendations in terms of study identification, data extraction, study quality appraisal and analytical plan. Although the ENCePP document should not be considered as definitive, since it will likely be refined following researchers’ feedback, it is expected that it will be highly influential and useful for the field, with the ultimate goal to improve and standardise the conduction and reporting of systematic reviews/meta-analyses of pharmacoepidemiological studies of safety outcomes.
425-427
Cortese, S.
53d4bf2c-4e0e-4c77-9385-218350560fdb
October 2016
Cortese, S.
53d4bf2c-4e0e-4c77-9385-218350560fdb
Cortese, S.
(2016)
Guidance on conducting systematic reviews/meta-analyses of pharmacoepidemiological studies of safety outcomes: the gap is now filled.
Epidemiology and Psychiatric Sciences, 25 (5), .
(doi:10.1017/S2045796016000299).
(PMID:27118442)
Abstract
Until recently, no comprehensive guidance specifically on the conduction of systematic reviews and meta-analyses of pharmacoepidemiological studies of safety outcomes was available. In December 2015, the European Network of Centres for Pharmacoepidemiology and Pharamacovigilance (ENCePP), a network coordinated by the European Medicines Agency, published their ‘Guidance on conducting systematic reviews and meta-analyses of completed comparative pharmacoepidemiological studies of safety outcomes’, filling an important gap in the field. This paper highlights the ENCePP recommendations in terms of study identification, data extraction, study quality appraisal and analytical plan. Although the ENCePP document should not be considered as definitive, since it will likely be refined following researchers’ feedback, it is expected that it will be highly influential and useful for the field, with the ultimate goal to improve and standardise the conduction and reporting of systematic reviews/meta-analyses of pharmacoepidemiological studies of safety outcomes.
Text
Cortese_EPS_2016.doc
- Accepted Manuscript
More information
Accepted/In Press date: 5 April 2016
e-pub ahead of print date: 27 April 2016
Published date: October 2016
Organisations:
Clinical Neuroscience
Identifiers
Local EPrints ID: 394819
URI: http://eprints.soton.ac.uk/id/eprint/394819
ISSN: 2045-7960
PURE UUID: c398d83c-b128-4cdd-a828-10925a317d07
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Date deposited: 24 May 2016 11:35
Last modified: 15 Mar 2024 03:52
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