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Microvesicles as biomarkers in diabetes, obesity and non-alcoholic fatty liver disease: current knowledge and future directions

Microvesicles as biomarkers in diabetes, obesity and non-alcoholic fatty liver disease: current knowledge and future directions
Microvesicles as biomarkers in diabetes, obesity and non-alcoholic fatty liver disease: current knowledge and future directions
NAFLD is the most common chronic liver disease, frequently associated with diabetes. Both of these insulin resistant states have increased cardiovascular risk factors associated, and a prevalent cause of mortality in these diseases. Microvesicles are heterogonously sized, phospholipid rich spheres released by cells upon activation and apoptosis. Evidence is continuing to accumulate of microvesicles being not only markers of disease severity but as also having a functional role in the pathophysiology of disease progression.
1-7
Welsh, Joshua
fd455949-5aab-442f-83f4-74ff62f41635
Holloway, Judith
f22f45f3-6fc8-4a4c-bc6c-24add507037c
Englyst, Nicola
f84399af-7265-4224-b556-102c3aa272b0
Welsh, Joshua
fd455949-5aab-442f-83f4-74ff62f41635
Holloway, Judith
f22f45f3-6fc8-4a4c-bc6c-24add507037c
Englyst, Nicola
f84399af-7265-4224-b556-102c3aa272b0

Welsh, Joshua, Holloway, Judith and Englyst, Nicola (2014) Microvesicles as biomarkers in diabetes, obesity and non-alcoholic fatty liver disease: current knowledge and future directions. Internal Medicine, S6 (9), 1-7. (doi:10.4172/2165-8048.S6-009).

Record type: Article

Abstract

NAFLD is the most common chronic liver disease, frequently associated with diabetes. Both of these insulin resistant states have increased cardiovascular risk factors associated, and a prevalent cause of mortality in these diseases. Microvesicles are heterogonously sized, phospholipid rich spheres released by cells upon activation and apoptosis. Evidence is continuing to accumulate of microvesicles being not only markers of disease severity but as also having a functional role in the pathophysiology of disease progression.

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microvesicles-as-biomarkers-in-diabetes-obesity-and-nonalcoholic-fatty-liver-disease-current-knowledge-and-future-directions-2165-8048.S6-009.pdf - Version of Record
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Accepted/In Press date: 21 October 2014
Published date: 29 October 2014
Related URLs:
Organisations: Human Development & Health

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Local EPrints ID: 395326
URI: http://eprints.soton.ac.uk/id/eprint/395326
DOI: doi:10.4172/2165-8048.S6-009
PURE UUID: d2ca752f-7111-4526-8139-8de7380b32cf
ORCID for Judith Holloway: ORCID iD orcid.org/0000-0002-2268-3071
ORCID for Nicola Englyst: ORCID iD orcid.org/0000-0003-0508-8323

Catalogue record

Date deposited: 27 May 2016 09:28
Last modified: 15 Mar 2024 03:05

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Contributors

Author: Joshua Welsh
Author: Judith Holloway ORCID iD
Author: Nicola Englyst ORCID iD

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