Highly diastereoselective synthesis of spiropyrazolones

Ceban, Victor, Olomola, Temitope, Meazza, Marta and Rios Torres, Ramon (2015) Highly diastereoselective synthesis of spiropyrazolones. Molecules, 20 (5), 8574-8582. (doi:10.3390/molecules20058574). (PMID:25985358)

Record type: Article

Abstract

We report a highly diastereoselective synthesis of spiropyrazolones catalyzed by secondary amines. The reported Michael-Aldol cascade reaction affords the desired spiropyrazolones bearing four chiral centers as a single diastereomer in excellent yields.

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Accepted/In Press date: 11 May 2015

Published date: 13 May 2015

Organisations: Organic Chemistry: Synthesis, Catalysis and Flow

Identifiers

Local EPrints ID: 395916

URI: http://eprints.soton.ac.uk/id/eprint/395916

DOI: doi:10.3390/molecules20058574

PURE UUID: 3eaac727-77f3-4ac8-8cf5-bb6fa6041dcf

ORCID for Marta Meazza:

orcid.org/0000-0003-4382-0626

ORCID for Ramon Rios Torres:

orcid.org/0000-0002-3843-8521

Catalogue record

Date deposited: 02 Jun 2016 08:33

Last modified: 15 Mar 2024 00:44

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Contributors

Author: Victor Ceban

Author: Temitope Olomola

Author: Marta Meazza

Author: Ramon Rios Torres

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