Use of CA-125 to define progression of ovarian cancer in patients with persistently elevated levels
Use of CA-125 to define progression of ovarian cancer in patients with persistently elevated levels
In patients whose CA-125 level decreases to normal after chemotherapy, a doubling from the upper limit of normal has been shown to predict progression. In those with persistently elevated levels, doubling of CA-125 from its nadir level has now been shown to accurately define progression. If confirmed, these CA-125 criteria should be used as additional end points in clinical trials.
4054-4057
Rustin, G.J.
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Marples, M.
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Nelstrop, A.E.
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Mahmoudi, M.
1dfae087-fe15-4e03-9f1a-510a4a84a6d5
Meyer, T.
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15 October 2001
Rustin, G.J.
6a670dea-00b6-4b57-9ca4-c4f3c45eaf3c
Marples, M.
df6d2e8c-017d-4786-930f-bbbf90c14a9a
Nelstrop, A.E.
6bbdffea-685f-40b9-bf86-e6bce683fde0
Mahmoudi, M.
1dfae087-fe15-4e03-9f1a-510a4a84a6d5
Meyer, T.
8ac918a9-e659-4d8e-8ada-7c0b205b54e6
Rustin, G.J., Marples, M., Nelstrop, A.E., Mahmoudi, M. and Meyer, T.
(2001)
Use of CA-125 to define progression of ovarian cancer in patients with persistently elevated levels.
Journal of Clinical Oncology, 19 (20), .
(PMID:11600607)
Abstract
In patients whose CA-125 level decreases to normal after chemotherapy, a doubling from the upper limit of normal has been shown to predict progression. In those with persistently elevated levels, doubling of CA-125 from its nadir level has now been shown to accurately define progression. If confirmed, these CA-125 criteria should be used as additional end points in clinical trials.
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Accepted/In Press date: 1 June 2001
Published date: 15 October 2001
Organisations:
Human Development & Health
Identifiers
Local EPrints ID: 396167
URI: http://eprints.soton.ac.uk/id/eprint/396167
ISSN: 1527-7755
PURE UUID: fac126d0-16a7-4d12-8b8b-364bd388be77
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Date deposited: 15 Jul 2016 15:48
Last modified: 22 Jul 2022 19:57
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Contributors
Author:
G.J. Rustin
Author:
M. Marples
Author:
A.E. Nelstrop
Author:
M. Mahmoudi
Author:
T. Meyer
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