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Impact of clinical osteoarthritis of the hip, knee and hand on self-rated health in six European countries: the European Project on OSteoArthritis

Impact of clinical osteoarthritis of the hip, knee and hand on self-rated health in six European countries: the European Project on OSteoArthritis
Impact of clinical osteoarthritis of the hip, knee and hand on self-rated health in six European countries: the European Project on OSteoArthritis
Purpose

Osteoarthritis (OA) has been shown to be associated with decreased physical function, which may impact upon a person’s self-rated health (SRH). Only a few studies have examined the association between OA and SRH in the general population, but to date none have used a clinical definition of OA. The objectives are: (1) To examine the cross-sectional association between clinical OA and fair-to-poor SRH in the general population; (2) To examine whether this association differs between countries; (3) To examine whether physical function is a mediator in the association between clinical OA and SRH.

Methods

Baseline data of the European Project on OSteoArthritis (EPOSA) were used, which includes pre-harmonized data from six European cohort studies (n = 2709). Clinical OA was defined according to the American College of Rheumatology criteria. SRH was assessed using one question: How is your health in general? Physical function was assessed using the Western Ontario and McMaster Universities OA Index and Australian/Canadian OA Hand Index.

Results

The prevalence of fair-to-poor SRH ranged from 19.8 % in the United Kingdom to 63.5 % in Italy. Although country differences in the strength of the associations were observed, clinical OA of the hip, knee and hand were significantly associated with fair-to-poor SRH in five out of six European countries. In most countries and at most sites, the association between clinical OA and fair-to-poor SRH was partly or fully mediated by physical function.

Conclusions

Clinical OA at different sites was related to fair-to-poor SRH in the general population. Most associations were (partly) mediated by physical functioning, indicating that deteriorating physical function in patients with OA should be a point of attention in patient care.
europe, general population, osteoarthritis, self-rated health
0962-9343
1423-1432
van Schoor, N.M.
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Zambon, S.
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Castell, M.V.
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Cooper, C.
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Dekinger, M.
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Dennison, E.
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Edwards, M.
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Herbolsheimer, F.
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Maggi, S.
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Sanchez-Martinez, M.
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Pedersen, N.L.
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Peter, R.
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Schaap, L.A.
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Rijhart, J.J.M.
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van der Pas, S.
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Deeg, D.J.H.
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van Schoor, N.M.
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Zambon, S.
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Castell, M.V.
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Cooper, C.
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Dekinger, M.
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Dennison, E.
ee647287-edb4-4392-8361-e59fd505b1d1
Edwards, M.
c9675e8c-09da-42df-be29-6be2dd524822
Herbolsheimer, F.
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Maggi, S.
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Sanchez-Martinez, M.
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Pedersen, N.L.
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Peter, R.
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Schaap, L.A.
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Rijhart, J.J.M.
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van der Pas, S.
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Deeg, D.J.H.
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van Schoor, N.M., Zambon, S., Castell, M.V., Cooper, C., Dekinger, M., Dennison, E., Edwards, M., Herbolsheimer, F., Maggi, S., Sanchez-Martinez, M., Pedersen, N.L., Peter, R., Schaap, L.A., Rijhart, J.J.M., van der Pas, S. and Deeg, D.J.H. (2016) Impact of clinical osteoarthritis of the hip, knee and hand on self-rated health in six European countries: the European Project on OSteoArthritis. Quality of Life Research, 25 (6), 1423-1432. (doi:10.1007/s11136-015-1171-8). (PMID:26547441)

Record type: Article

Abstract

Purpose

Osteoarthritis (OA) has been shown to be associated with decreased physical function, which may impact upon a person’s self-rated health (SRH). Only a few studies have examined the association between OA and SRH in the general population, but to date none have used a clinical definition of OA. The objectives are: (1) To examine the cross-sectional association between clinical OA and fair-to-poor SRH in the general population; (2) To examine whether this association differs between countries; (3) To examine whether physical function is a mediator in the association between clinical OA and SRH.

Methods

Baseline data of the European Project on OSteoArthritis (EPOSA) were used, which includes pre-harmonized data from six European cohort studies (n = 2709). Clinical OA was defined according to the American College of Rheumatology criteria. SRH was assessed using one question: How is your health in general? Physical function was assessed using the Western Ontario and McMaster Universities OA Index and Australian/Canadian OA Hand Index.

Results

The prevalence of fair-to-poor SRH ranged from 19.8 % in the United Kingdom to 63.5 % in Italy. Although country differences in the strength of the associations were observed, clinical OA of the hip, knee and hand were significantly associated with fair-to-poor SRH in five out of six European countries. In most countries and at most sites, the association between clinical OA and fair-to-poor SRH was partly or fully mediated by physical function.

Conclusions

Clinical OA at different sites was related to fair-to-poor SRH in the general population. Most associations were (partly) mediated by physical functioning, indicating that deteriorating physical function in patients with OA should be a point of attention in patient care.

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Osteoarthritis and self-rated health revised 2 def marked.doc - Accepted Manuscript
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More information

Accepted/In Press date: 28 October 2015
e-pub ahead of print date: 7 November 2015
Published date: June 2016
Keywords: europe, general population, osteoarthritis, self-rated health
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 396656
URI: http://eprints.soton.ac.uk/id/eprint/396656
ISSN: 0962-9343
PURE UUID: 4617e6fc-b04d-4f54-99da-493f87e29180
ORCID for C. Cooper: ORCID iD orcid.org/0000-0003-3510-0709
ORCID for E. Dennison: ORCID iD orcid.org/0000-0002-3048-4961

Catalogue record

Date deposited: 10 Jun 2016 14:19
Last modified: 18 Feb 2021 16:48

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Contributors

Author: N.M. van Schoor
Author: S. Zambon
Author: M.V. Castell
Author: C. Cooper ORCID iD
Author: M. Dekinger
Author: E. Dennison ORCID iD
Author: M. Edwards
Author: F. Herbolsheimer
Author: S. Maggi
Author: M. Sanchez-Martinez
Author: N.L. Pedersen
Author: R. Peter
Author: L.A. Schaap
Author: J.J.M. Rijhart
Author: S. van der Pas
Author: D.J.H. Deeg

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