Synthesis and gelation properties of poly(2-alkyl-2-oxazoline) based thermo-gels
Synthesis and gelation properties of poly(2-alkyl-2-oxazoline) based thermo-gels
A series of new thermo-gelling polymers based on thermo-responsive poly(2-alkyl-2-oxazoline)s has been prepared by grafting different poly(2-alkyl-2-oxazolines) onto a polar carboxymethylcellulose backbone. Thermo-reversible gelation is observed at low concentrations (less than 5% by weight of thermo-gelling polymer). Rheology reveals that these polymers show tuneable gelation temperatures, which vary with concentration and poly(2-oxazoline) composition. This allows the gelation point to be adjusted to biologically relevant temperatures, offering a novel material with potential applications in areas such as drug delivery and tissue engineering.
66438-66443
Fisher, Adam
0cbfd7a8-a475-45eb-bf51-3f5377645c51
Schollick, Julia M.H.
a8ccb7e7-6ad5-4056-b09b-090d9bc03006
Aarts, Dirk G.A.L.
25df0453-ed9e-4373-a234-b95c8d4bc80e
Grossel, Martin
403bf3ff-6364-44e9-ab46-52d84c6f0d56
Fisher, Adam
0cbfd7a8-a475-45eb-bf51-3f5377645c51
Schollick, Julia M.H.
a8ccb7e7-6ad5-4056-b09b-090d9bc03006
Aarts, Dirk G.A.L.
25df0453-ed9e-4373-a234-b95c8d4bc80e
Grossel, Martin
403bf3ff-6364-44e9-ab46-52d84c6f0d56
Fisher, Adam, Schollick, Julia M.H., Aarts, Dirk G.A.L. and Grossel, Martin
(2016)
Synthesis and gelation properties of poly(2-alkyl-2-oxazoline) based thermo-gels.
RSC Advances, 6 (71), .
(doi:10.1039/C6RA06781F).
Abstract
A series of new thermo-gelling polymers based on thermo-responsive poly(2-alkyl-2-oxazoline)s has been prepared by grafting different poly(2-alkyl-2-oxazolines) onto a polar carboxymethylcellulose backbone. Thermo-reversible gelation is observed at low concentrations (less than 5% by weight of thermo-gelling polymer). Rheology reveals that these polymers show tuneable gelation temperatures, which vary with concentration and poly(2-oxazoline) composition. This allows the gelation point to be adjusted to biologically relevant temperatures, offering a novel material with potential applications in areas such as drug delivery and tissue engineering.
Text
__soton.ac.uk_ude_personalfiles_users_jks1m11_mydesktop_RSC Advances final Revised June V2-2 Adam Revised Final Dptal.pdf
- Accepted Manuscript
More information
Accepted/In Press date: 3 July 2016
e-pub ahead of print date: 4 July 2016
Organisations:
Organic Chemistry: Synthesis, Catalysis and Flow
Identifiers
Local EPrints ID: 397997
URI: http://eprints.soton.ac.uk/id/eprint/397997
ISSN: 2046-2069
PURE UUID: 86e40456-77dc-4c0d-aefa-12a4d9af1096
Catalogue record
Date deposited: 14 Jul 2016 08:48
Last modified: 15 Mar 2024 05:44
Export record
Altmetrics
Contributors
Author:
Adam Fisher
Author:
Julia M.H. Schollick
Author:
Dirk G.A.L. Aarts
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
