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Frailty predicts trajectories of quality of life over time among British community-dwelling older people

Frailty predicts trajectories of quality of life over time among British community-dwelling older people
Frailty predicts trajectories of quality of life over time among British community-dwelling older people
Purpose

To investigate associations between baseline frailty status and subsequent changes in QOL over time among community-dwelling older people.

Methods

Among 363 community-dwelling older people ?65 years, frailty was measured using Frailty Index (FI) constructed from 40 deficits at baseline. QOL was measured using Older People’s Quality of Life Questionnaire (OPQOL) six times over 2.5 years. Two-level hierarchical linear models were employed to predict QOL changes over time according to baseline frailty.

Results

At baseline, mean age was 73.1 (range 65–90) and 62.0 % were women. Mean FI was 0.17 (range 0.00–0.66), and mean OPQOL was 130.80 (range 93–163). The hierarchical linear model adjusted for age, gender, ethnicity, education, and enrollment site predicted that those with higher FI at baseline have lower QOL than those with lower FI (regression coefficient = ?47.64, p < 0.0001) and that QOL changes linearly over time with slopes ranging from 0.80 (FI = 0.00) to ?1.15 (FI = 0.66) as the FI increases. A FI of 0.27 is the cutoff point at which improvements in QOL over time change to declines in QOL.

Conclusions

Frailty was associated with lower QOL among British community-dwelling older people. While less frail participants had higher QOL at baseline and QOL improved over time, QOL of frailer participants was lower at baseline and declined.
frailty, quality of life, well-being, community-dwelling older people
0962-9343
1743-1750
Kojima, Gotaro
6ed8154b-d8a8-4caf-87ae-35d1f1d2d750
Iliffe, Steve
3608ad54-c5c6-44c3-8ea8-011412b6c78d
Morris, Richard W.
db5b905e-be9a-439c-bdee-47b01a953e7e
Taniguchi, Yu
f695f1a7-3505-4114-ac09-78bbc3c6fd0c
Kendrick, Denise
33ad9db9-6d98-4e87-a2ad-323b289e3a16
Skelton, Dawn A.
aa97ecd5-76c1-488a-bb40-98f815e920ab
Masud, Tahir
ef1fc17c-f133-4635-82bb-547b58521ceb
Bowling, Ann
796ca209-687f-4079-8a40-572076251936
Kojima, Gotaro
6ed8154b-d8a8-4caf-87ae-35d1f1d2d750
Iliffe, Steve
3608ad54-c5c6-44c3-8ea8-011412b6c78d
Morris, Richard W.
db5b905e-be9a-439c-bdee-47b01a953e7e
Taniguchi, Yu
f695f1a7-3505-4114-ac09-78bbc3c6fd0c
Kendrick, Denise
33ad9db9-6d98-4e87-a2ad-323b289e3a16
Skelton, Dawn A.
aa97ecd5-76c1-488a-bb40-98f815e920ab
Masud, Tahir
ef1fc17c-f133-4635-82bb-547b58521ceb
Bowling, Ann
796ca209-687f-4079-8a40-572076251936

Kojima, Gotaro, Iliffe, Steve, Morris, Richard W., Taniguchi, Yu, Kendrick, Denise, Skelton, Dawn A., Masud, Tahir and Bowling, Ann (2016) Frailty predicts trajectories of quality of life over time among British community-dwelling older people. Quality of Life Research, 25 (7), 1743-1750. (doi:10.1007/s11136-015-1213-2). (PMID:26747318)

Record type: Article

Abstract

Purpose

To investigate associations between baseline frailty status and subsequent changes in QOL over time among community-dwelling older people.

Methods

Among 363 community-dwelling older people ?65 years, frailty was measured using Frailty Index (FI) constructed from 40 deficits at baseline. QOL was measured using Older People’s Quality of Life Questionnaire (OPQOL) six times over 2.5 years. Two-level hierarchical linear models were employed to predict QOL changes over time according to baseline frailty.

Results

At baseline, mean age was 73.1 (range 65–90) and 62.0 % were women. Mean FI was 0.17 (range 0.00–0.66), and mean OPQOL was 130.80 (range 93–163). The hierarchical linear model adjusted for age, gender, ethnicity, education, and enrollment site predicted that those with higher FI at baseline have lower QOL than those with lower FI (regression coefficient = ?47.64, p < 0.0001) and that QOL changes linearly over time with slopes ranging from 0.80 (FI = 0.00) to ?1.15 (FI = 0.66) as the FI increases. A FI of 0.27 is the cutoff point at which improvements in QOL over time change to declines in QOL.

Conclusions

Frailty was associated with lower QOL among British community-dwelling older people. While less frail participants had higher QOL at baseline and QOL improved over time, QOL of frailer participants was lower at baseline and declined.

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More information

Accepted/In Press date: 12 December 2015
e-pub ahead of print date: 9 January 2016
Published date: 9 January 2016
Keywords: frailty, quality of life, well-being, community-dwelling older people
Organisations: Faculty of Health Sciences

Identifiers

Local EPrints ID: 399167
URI: http://eprints.soton.ac.uk/id/eprint/399167
ISSN: 0962-9343
PURE UUID: 9f5e23c9-9559-4c2d-85a8-38a299131b78

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Date deposited: 09 Aug 2016 14:23
Last modified: 15 Mar 2024 01:46

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Contributors

Author: Gotaro Kojima
Author: Steve Iliffe
Author: Richard W. Morris
Author: Yu Taniguchi
Author: Denise Kendrick
Author: Dawn A. Skelton
Author: Tahir Masud
Author: Ann Bowling

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