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Fatty acid status and antioxidant defence system in mothers and their newborns after salmon intake during late pregnancy

Fatty acid status and antioxidant defence system in mothers and their newborns after salmon intake during late pregnancy
Fatty acid status and antioxidant defence system in mothers and their newborns after salmon intake during late pregnancy
Objective: The aim of the present study was to assess the maternal and newborn status of erythrocyte fatty acids and the antioxidant defense system after the intake of two portions of salmon per week during late pregnancy.

Methods: Pregnant women (N = 123) were randomly assigned to continue their habitual diet, which was low in oily fish (control group, n = 61) or to consume two 150-g salmon portions per week (salmon group, n = 62) beginning at 20 wk of gestation and lasting until delivery. Fatty acids, selenium, and glutathione concentrations and antioxidant defense enzyme activities were measured in maternal erythrocytes at 20, 34, and 38 wk of pregnancy, and in cord erythrocytes collected at birth. Plasma concentrations of antioxidant molecules were measured.

Results: Compared with the control group, consuming salmon had little effect on erythrocyte fatty acids in either mothers or newborns. Components of the antioxidant defense system did not differ between groups. Glutathione peroxidase activity and the concentrations of tocopherols, retinol, and coenzyme Q10 were significantly lower in cord blood compared with maternal blood at week 38 in both groups.

Conclusion: Maternal and newborn erythrocyte fatty acids are not strongly affected by the intake of two portions of salmon per week during the second half of pregnancy, although erythrocyte docosahexaenoic acid might be increased in newborns. Maternal and newborn antioxidant defense systems are not impaired by intake of salmon from 20 wk gestation.
0899-9007
157-162
Garcia-Rodriguez, C.E.
adb2ae85-2423-4c32-99e3-3fcd7dba6053
Olza, J.
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Mesa, M.D.
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Aguilera, C.M.
48ace556-48e3-4276-a581-d41309869acd
Miles, E.A.
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Noakes, P.S.
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Vlachava, M.
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Kremmyda, L.-S.
e74b9ec3-a5aa-4bb4-8dd7-bcb393bad326
Diaper, N.D.
4fb72117-ec04-48e9-b375-3eb5cb4997f5
Godfrey, K.M.
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Calder, P.C.
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Gil, A.
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Garcia-Rodriguez, C.E.
adb2ae85-2423-4c32-99e3-3fcd7dba6053
Olza, J.
be055e8c-1299-4e5c-b630-b4a74a0f76cd
Mesa, M.D.
5db8da44-fdd8-48a8-8e25-0d62c6585fda
Aguilera, C.M.
48ace556-48e3-4276-a581-d41309869acd
Miles, E.A.
20332899-ecdb-4214-95bc-922dde36d416
Noakes, P.S.
0ed50cd9-de73-4851-8039-ee72860d8ae5
Vlachava, M.
e24c6fcd-7f45-4059-bd6b-3cb7398eef58
Kremmyda, L.-S.
e74b9ec3-a5aa-4bb4-8dd7-bcb393bad326
Diaper, N.D.
4fb72117-ec04-48e9-b375-3eb5cb4997f5
Godfrey, K.M.
0931701e-fe2c-44b5-8f0d-ec5c7477a6fd
Calder, P.C.
1797e54f-378e-4dcb-80a4-3e30018f07a6
Gil, A.
23629506-bec6-4b0c-8608-4ff63ee20013

Garcia-Rodriguez, C.E., Olza, J., Mesa, M.D., Aguilera, C.M., Miles, E.A., Noakes, P.S., Vlachava, M., Kremmyda, L.-S., Diaper, N.D., Godfrey, K.M., Calder, P.C. and Gil, A. (2017) Fatty acid status and antioxidant defence system in mothers and their newborns after salmon intake during late pregnancy. Nutrition, 33, 157-162. (doi:10.1016/j.nut.2016.05.015). (PMID:27497519)

Record type: Article

Abstract

Objective: The aim of the present study was to assess the maternal and newborn status of erythrocyte fatty acids and the antioxidant defense system after the intake of two portions of salmon per week during late pregnancy.

Methods: Pregnant women (N = 123) were randomly assigned to continue their habitual diet, which was low in oily fish (control group, n = 61) or to consume two 150-g salmon portions per week (salmon group, n = 62) beginning at 20 wk of gestation and lasting until delivery. Fatty acids, selenium, and glutathione concentrations and antioxidant defense enzyme activities were measured in maternal erythrocytes at 20, 34, and 38 wk of pregnancy, and in cord erythrocytes collected at birth. Plasma concentrations of antioxidant molecules were measured.

Results: Compared with the control group, consuming salmon had little effect on erythrocyte fatty acids in either mothers or newborns. Components of the antioxidant defense system did not differ between groups. Glutathione peroxidase activity and the concentrations of tocopherols, retinol, and coenzyme Q10 were significantly lower in cord blood compared with maternal blood at week 38 in both groups.

Conclusion: Maternal and newborn erythrocyte fatty acids are not strongly affected by the intake of two portions of salmon per week during the second half of pregnancy, although erythrocyte docosahexaenoic acid might be increased in newborns. Maternal and newborn antioxidant defense systems are not impaired by intake of salmon from 20 wk gestation.

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Accepted/In Press date: 25 May 2016
e-pub ahead of print date: 8 June 2016
Published date: January 2017
Organisations: Human Development & Health

Identifiers

Local EPrints ID: 399304
URI: http://eprints.soton.ac.uk/id/eprint/399304
ISSN: 0899-9007
PURE UUID: 04bfd47a-545d-4369-b342-5e4d7c918966
ORCID for E.A. Miles: ORCID iD orcid.org/0000-0002-8643-0655
ORCID for P.S. Noakes: ORCID iD orcid.org/0000-0002-2678-1971
ORCID for K.M. Godfrey: ORCID iD orcid.org/0000-0002-4643-0618
ORCID for P.C. Calder: ORCID iD orcid.org/0000-0002-6038-710X

Catalogue record

Date deposited: 15 Aug 2016 10:13
Last modified: 15 Mar 2024 05:48

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Contributors

Author: C.E. Garcia-Rodriguez
Author: J. Olza
Author: M.D. Mesa
Author: C.M. Aguilera
Author: E.A. Miles ORCID iD
Author: P.S. Noakes ORCID iD
Author: M. Vlachava
Author: L.-S. Kremmyda
Author: N.D. Diaper
Author: K.M. Godfrey ORCID iD
Author: P.C. Calder ORCID iD
Author: A. Gil

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