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Alpha-3 chain type IV collagen polypeptides

Alpha-3 chain type IV collagen polypeptides
Alpha-3 chain type IV collagen polypeptides
An isolated and substantially pure polynucleotide encoding 238 amino acids of the carboxy terminal end of the triple helical domain and all 233 amino acids of the carboxy terminal noncollageneous domain of the bovine .alpha.3 chain of type IV collagen. An isolated and substantially pure polynucleotide encoding 218 amino acids of the carboxy terminal noncollagenous domain of the human .alpha.3 chain of type IV collagen. Such polynucleotides are useful to express large amounts of proteins in vectors and such expressed proteins are useful to detect Goodpasture antibodies in blood and to remove Goodpasture antibodies from the bloodstream of patients suffering from Goodpasture syndrome.
US6,007,980
Reeders, Stephen T.
7a905a1a-d6de-49dd-a5be-ded5220fd725
Morrison, Karen E.
f00890f0-2fde-4dbd-a73b-7422e1b0ede8
Hudson, Billy G.
8d09869e-2eeb-4349-b3fd-2de782a77cda

Reeders, Stephen T., Morrison, Karen E. and Hudson, Billy G. (Inventors) (1999) Alpha-3 chain type IV collagen polypeptides. US6,007,980.

Record type: Patent

Abstract

An isolated and substantially pure polynucleotide encoding 238 amino acids of the carboxy terminal end of the triple helical domain and all 233 amino acids of the carboxy terminal noncollageneous domain of the bovine .alpha.3 chain of type IV collagen. An isolated and substantially pure polynucleotide encoding 218 amino acids of the carboxy terminal noncollagenous domain of the human .alpha.3 chain of type IV collagen. Such polynucleotides are useful to express large amounts of proteins in vectors and such expressed proteins are useful to detect Goodpasture antibodies in blood and to remove Goodpasture antibodies from the bloodstream of patients suffering from Goodpasture syndrome.

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More information

Published date: 28 December 1999
Organisations: Medical Education

Identifiers

Local EPrints ID: 399579
URI: http://eprints.soton.ac.uk/id/eprint/399579
PURE UUID: de6c1ae1-57aa-40c5-aca9-7b69c261a29d
ORCID for Karen E. Morrison: ORCID iD orcid.org/0000-0003-0216-5717

Catalogue record

Date deposited: 18 Aug 2016 14:11
Last modified: 06 Jun 2018 12:19

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Contributors

Inventor: Stephen T. Reeders
Inventor: Karen E. Morrison ORCID iD
Inventor: Billy G. Hudson

University divisions

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