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Multicolor imaging in the diagnosis and follow up of type 2 acute macular neuro-retinopathy

Multicolor imaging in the diagnosis and follow up of type 2 acute macular neuro-retinopathy
Multicolor imaging in the diagnosis and follow up of type 2 acute macular neuro-retinopathy
Purpose
To study the usefulness of multicolor imaging (MC) photographs in addition to near infrared reflectance (NIR) and spectral domain optical coherence tomography (SD-OCT) in the detection and follow up of acute macular neuroretinopathy (AMN).

Patients and methods
Six patients with a complaint of paracentral scotomas in at least one eye due to AMN were included. They underwent full ophthalmic examination and multimodal imaging including color fundus photographs, (SD-OCT), NIR, and MC at baseline and follow up.

Results
Four females and two males, aged 19–64 years, and eight eyes affected by AMN, were included. Acute phase SD-OCT in all patients confirmed the diagnosis of type 2 AMN with partial recovery of the outer retina in the convalescent phase. NIR and MC elicited in all cases hypo-reflective AMN lesions pointing toward the fovea. MC exhibited a higher contrast between the affected and the physiologic retina that slowly attenuated during the follow up showing a decrease in the hypo-reflectance of the lesions.

Conclusion
MC imaging was more detailed than fundus color photographs and as detailed as NIR in the detection of AMN. When available, MC imaging should complement SD-OCT and NIR in the diagnosis and follow up of this rare inflammatory condition that may be underdiagnosed.
0950-222X
127–131
De Salvo, Gabriella
a747876b-c03d-4655-b31c-735e0f2920d2
Vaz-Pereira, Sara
49114ee4-8c8d-45cb-8cf9-6ae09ee1610c
Arora, Rashi
721f0e75-79d2-44e0-b8a1-5df7850658b9
Lotery, Andrew J.
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514
De Salvo, Gabriella
a747876b-c03d-4655-b31c-735e0f2920d2
Vaz-Pereira, Sara
49114ee4-8c8d-45cb-8cf9-6ae09ee1610c
Arora, Rashi
721f0e75-79d2-44e0-b8a1-5df7850658b9
Lotery, Andrew J.
5ecc2d2d-d0b4-468f-ad2c-df7156f8e514

De Salvo, Gabriella, Vaz-Pereira, Sara, Arora, Rashi and Lotery, Andrew J. (2017) Multicolor imaging in the diagnosis and follow up of type 2 acute macular neuro-retinopathy. Eye, 31 (1), 127–131. (doi:10.1038/eye.2016.193).

Record type: Article

Abstract

Purpose
To study the usefulness of multicolor imaging (MC) photographs in addition to near infrared reflectance (NIR) and spectral domain optical coherence tomography (SD-OCT) in the detection and follow up of acute macular neuroretinopathy (AMN).

Patients and methods
Six patients with a complaint of paracentral scotomas in at least one eye due to AMN were included. They underwent full ophthalmic examination and multimodal imaging including color fundus photographs, (SD-OCT), NIR, and MC at baseline and follow up.

Results
Four females and two males, aged 19–64 years, and eight eyes affected by AMN, were included. Acute phase SD-OCT in all patients confirmed the diagnosis of type 2 AMN with partial recovery of the outer retina in the convalescent phase. NIR and MC elicited in all cases hypo-reflective AMN lesions pointing toward the fovea. MC exhibited a higher contrast between the affected and the physiologic retina that slowly attenuated during the follow up showing a decrease in the hypo-reflectance of the lesions.

Conclusion
MC imaging was more detailed than fundus color photographs and as detailed as NIR in the detection of AMN. When available, MC imaging should complement SD-OCT and NIR in the diagnosis and follow up of this rare inflammatory condition that may be underdiagnosed.

Text
MC in AMN GDS clean version.doc - Accepted Manuscript
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More information

Accepted/In Press date: 11 July 2016
e-pub ahead of print date: 30 September 2016
Published date: January 2017
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 399728
URI: http://eprints.soton.ac.uk/id/eprint/399728
ISSN: 0950-222X
PURE UUID: 0219c138-efd2-4eaa-811e-b23edd45c077
ORCID for Andrew J. Lotery: ORCID iD orcid.org/0000-0001-5541-4305

Catalogue record

Date deposited: 24 Aug 2016 13:36
Last modified: 07 Oct 2020 04:56

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