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Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity

Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity
Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity
New oxathiazinane dioxides have been derived from d- and l-serine and tested for their in vitro cell growth inhibitory activity toward SKBR3 breast cancer cells. (5R)-5-(4-(4?-Bromomethyl)phenyl)benzyloxymethyl-[1,3,4]-oxathiazinane-3,3-dioxide showed a cytotoxicity of IC50 = 10 uM.
0960-894X
5353-5356
Borcard, Françoise
bc0c007f-cd83-4aaa-bb5d-3804c10cff5b
Baud, Matthias
8752d519-3d33-43b6-9a77-ab731d410c2e
Bello, Claudia
b799d5b0-e7a0-408b-a0a2-22fbf8c097e7
Dal Bello, Giovanna
6c630fb1-de98-42b2-8afc-221778bdf4c5
Grossi, Francesco
3c0c392c-d6dc-440a-95ce-b92866bb08e1
Pronzato, Paolo
6374af29-2c33-41f7-bad3-b05cb3c3b7fb
Cea, Michele
f9e3ec46-c7d1-43df-b8d1-ee2d07f9c259
Nencioni, Alessio
3d7ba8e1-fff3-4c39-94b8-510d59af44eb
Vogel, Pierre
f2987aa5-2f2d-48d7-83b8-bd1e02241909
Borcard, Françoise
bc0c007f-cd83-4aaa-bb5d-3804c10cff5b
Baud, Matthias
8752d519-3d33-43b6-9a77-ab731d410c2e
Bello, Claudia
b799d5b0-e7a0-408b-a0a2-22fbf8c097e7
Dal Bello, Giovanna
6c630fb1-de98-42b2-8afc-221778bdf4c5
Grossi, Francesco
3c0c392c-d6dc-440a-95ce-b92866bb08e1
Pronzato, Paolo
6374af29-2c33-41f7-bad3-b05cb3c3b7fb
Cea, Michele
f9e3ec46-c7d1-43df-b8d1-ee2d07f9c259
Nencioni, Alessio
3d7ba8e1-fff3-4c39-94b8-510d59af44eb
Vogel, Pierre
f2987aa5-2f2d-48d7-83b8-bd1e02241909

Borcard, Françoise, Baud, Matthias, Bello, Claudia, Dal Bello, Giovanna, Grossi, Francesco, Pronzato, Paolo, Cea, Michele, Nencioni, Alessio and Vogel, Pierre (2010) Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity. Bio-organic & Medicinal Chemistry Letters, 20 (17), 5353-5356. (doi:10.1016/j.bmcl.2009.09.019).

Record type: Article

Abstract

New oxathiazinane dioxides have been derived from d- and l-serine and tested for their in vitro cell growth inhibitory activity toward SKBR3 breast cancer cells. (5R)-5-(4-(4?-Bromomethyl)phenyl)benzyloxymethyl-[1,3,4]-oxathiazinane-3,3-dioxide showed a cytotoxicity of IC50 = 10 uM.

Full text not available from this repository.

More information

Accepted/In Press date: 4 September 2009
e-pub ahead of print date: 10 September 2009
Published date: 1 September 2010

Identifiers

Local EPrints ID: 400518
URI: https://eprints.soton.ac.uk/id/eprint/400518
ISSN: 0960-894X
PURE UUID: 1b9127a3-e9d8-4550-b5de-1e6bea5fea77
ORCID for Matthias Baud: ORCID iD orcid.org/0000-0003-3714-4350

Catalogue record

Date deposited: 21 Sep 2016 15:31
Last modified: 14 Jul 2018 00:28

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