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Novel biocompatible and resorbable UV transparent phosphate glass based optical fiber

Novel biocompatible and resorbable UV transparent phosphate glass based optical fiber
Novel biocompatible and resorbable UV transparent phosphate glass based optical fiber
In this paper the first glass based resorbable optical fiber is manufactured and characterized, showing values of attenuation loss from one to two orders of magnitude lower than the polymeric based bioresorbable devices reported in literature. The fiber behaves as a single-mode waveguide at the lower limit of the first biological window (1300 nm) and as a multi-mode waveguide in the visible region (630 nm). Highly transparent calcium-phosphate glasses (PGs) are proposed as a new class of materials for biomedical optics, managing to combine for the first time in a vitreous material solubility in aqueous media, transparency in the near UV region, low intrinsic attenuation loss and thermal stability during fiber drawing. In-vitro tests in physiological conditions show dissolution kinetics of glass fibers in about a month.
2040-2051
Ceci-Ginistrelli, Edoardo
9dd22634-87d6-4f74-b23f-87f7e9ba6f1e
Pugliese, Diego
8b64aacb-c498-4a44-8772-608300e5039f
Boetti, Nadia
277158b9-49e5-4084-8af3-5a1d1a462529
Novajra, Giorgia
7d266045-6ef2-4985-8f2f-d5d5ed777126
Ambrosone, Annarita
97f564bd-4932-4592-b1b1-129d5c2a4338
Lousteau, Joris
0758be5e-04e3-452f-81f9-7616cf4a3de3
Vitale-Brovarone, Chiara
32ff89df-a338-4ba0-a4cc-5345e9bf8b7d
Abrate, Silvio
10c03c84-cb3b-43be-ac47-71429467612c
Milanese, Daniel
115a5464-d0fb-49c7-892f-ae5a9ae1bd25
Ceci-Ginistrelli, Edoardo
9dd22634-87d6-4f74-b23f-87f7e9ba6f1e
Pugliese, Diego
8b64aacb-c498-4a44-8772-608300e5039f
Boetti, Nadia
277158b9-49e5-4084-8af3-5a1d1a462529
Novajra, Giorgia
7d266045-6ef2-4985-8f2f-d5d5ed777126
Ambrosone, Annarita
97f564bd-4932-4592-b1b1-129d5c2a4338
Lousteau, Joris
0758be5e-04e3-452f-81f9-7616cf4a3de3
Vitale-Brovarone, Chiara
32ff89df-a338-4ba0-a4cc-5345e9bf8b7d
Abrate, Silvio
10c03c84-cb3b-43be-ac47-71429467612c
Milanese, Daniel
115a5464-d0fb-49c7-892f-ae5a9ae1bd25

Ceci-Ginistrelli, Edoardo, Pugliese, Diego, Boetti, Nadia, Novajra, Giorgia, Ambrosone, Annarita, Lousteau, Joris, Vitale-Brovarone, Chiara, Abrate, Silvio and Milanese, Daniel (2016) Novel biocompatible and resorbable UV transparent phosphate glass based optical fiber. Optical Materials Express, 6 (6), 2040-2051. (doi:10.1364/OME.6.002040).

Record type: Article

Abstract

In this paper the first glass based resorbable optical fiber is manufactured and characterized, showing values of attenuation loss from one to two orders of magnitude lower than the polymeric based bioresorbable devices reported in literature. The fiber behaves as a single-mode waveguide at the lower limit of the first biological window (1300 nm) and as a multi-mode waveguide in the visible region (630 nm). Highly transparent calcium-phosphate glasses (PGs) are proposed as a new class of materials for biomedical optics, managing to combine for the first time in a vitreous material solubility in aqueous media, transparency in the near UV region, low intrinsic attenuation loss and thermal stability during fiber drawing. In-vitro tests in physiological conditions show dissolution kinetics of glass fibers in about a month.

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Accepted/In Press date: 18 May 2016
e-pub ahead of print date: 23 May 2016
Published date: June 2016
Organisations: Optoelectronics Research Centre

Identifiers

Local EPrints ID: 400773
URI: https://eprints.soton.ac.uk/id/eprint/400773
PURE UUID: 77cf665b-24ba-4f23-ab60-3de8bb941ee9

Catalogue record

Date deposited: 27 Sep 2016 09:27
Last modified: 05 Oct 2018 12:06

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