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Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus
Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus
This high throughput platform was able to successfully interrogate the methylation state of individual cytosines and identified 19 prospective CpG sites associated with risk of diabetic nephropathy. These differences in DNA methylation are worthy of further follow-up in replication studies using larger cohorts of diabetic patients with and without nephropathy
1755-8794
33
Bell, Christopher G.
44982df7-0746-4cdb-bed1-0bdfe68f1a64
Teschendorff, Andrew E.
b1d5937a-e56f-4fbf-8f38-70e756e2cdda
Rakyan, Vardhman K.
39c272f9-6ec7-4ac4-8c15-c80c8d936438
Maxwell, Alexander P.
1f5de478-59ba-4954-9ccf-28a15fe8dd8f
Beck, Stephan
50f0c07a-19a8-4bca-adbc-af41a3800412
Savage, David A.
234b6085-74f8-4543-b16d-6224a37eee42
Bell, Christopher G.
44982df7-0746-4cdb-bed1-0bdfe68f1a64
Teschendorff, Andrew E.
b1d5937a-e56f-4fbf-8f38-70e756e2cdda
Rakyan, Vardhman K.
39c272f9-6ec7-4ac4-8c15-c80c8d936438
Maxwell, Alexander P.
1f5de478-59ba-4954-9ccf-28a15fe8dd8f
Beck, Stephan
50f0c07a-19a8-4bca-adbc-af41a3800412
Savage, David A.
234b6085-74f8-4543-b16d-6224a37eee42

Bell, Christopher G., Teschendorff, Andrew E., Rakyan, Vardhman K., Maxwell, Alexander P., Beck, Stephan and Savage, David A. (2010) Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus. BMC Medical Genomics, 3, 33. (doi:10.1186/1755-8794-3-33). (PMID:19829295)

Record type: Article

Abstract

This high throughput platform was able to successfully interrogate the methylation state of individual cytosines and identified 19 prospective CpG sites associated with risk of diabetic nephropathy. These differences in DNA methylation are worthy of further follow-up in replication studies using larger cohorts of diabetic patients with and without nephropathy

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More information

Published date: 5 August 2010
Organisations: Human Development & Health, Centre for Biological Sciences, MRC Life-Course Epidemiology Unit

Identifiers

Local EPrints ID: 400990
URI: https://eprints.soton.ac.uk/id/eprint/400990
ISSN: 1755-8794
PURE UUID: a4967b14-27a4-434f-ba40-ef9014e9ec29
ORCID for Christopher G. Bell: ORCID iD orcid.org/0000-0003-4601-1242

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Date deposited: 03 Oct 2016 09:09
Last modified: 20 Jul 2019 00:34

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